GERI-BP002-A (CAS 119-47-1)
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GERI-BP002-A is a compound with notable interest in biochemical research due to its role as an inhibitor of acyl-CoA cholesterol acyltransferase (ACAT). In biochemical and cellular studies, GERI-BP002-A is utilized to explore the regulation of cholesterol metabolism. By inhibiting ACAT, it helps in dissecting the enzyme′s role in cholesterol esterification and the subsequent effect on lipid storage within cells. This compound is also valuable in the study of atherosclerosis, where cholesterol accumulation in arterial walls is a key factor, allowing researchers to investigate the underlying mechanisms of lipid homeostasis and its disruption. Furthermore, GERI-BP002-A is employed in research to understand the impact of ACAT inhibition on lipid-related conditions. Its efficacy in modulating ACAT activity also offers insights into the synthesis of intracellular lipid droplets and their influence on cellular functions.
GERI-BP002-A (CAS 119-47-1) References
- Phenylpyropene C, a new inhibitor of acyl-CoA: cholesterol acyltransferase produced by Penicillium griseofulvum F1959. | Rho, MC., et al. 2002. J Antibiot (Tokyo). 55: 211-4. PMID: 12003004
- Mast cell death induced by 24(S),25-epoxycholesterol. | Fukunaga, M., et al. 2010. Exp Cell Res. 316: 3272-81. PMID: 20854813
- GERI-BP002-A, novel inhibitor of acyl-CoA: cholesterol acyltransferase produced by Aspergillus fumigatus F93. | Kim, YK., et al. 1996. J Antibiot (Tokyo). 49: 31-6. PMID: 8609082
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GERI-BP002-A, 100 mg | sc-221667 | 100 mg | $43.00 | |||
GERI-BP002-A, 1 g | sc-221667A | 1 g | $102.00 |