Snk inhibitors are a class of chemical compounds that primarily target a specific group of enzymes known as serine/threonine kinases (Snk). Serine/threonine kinases are a vital component of cellular signaling pathways, playing a crucial role in the regulation of various cellular processes, including cell growth, proliferation, differentiation, and apoptosis. These enzymes are essential for maintaining cellular homeostasis and ensuring proper responses to external stimuli. The inhibition of Snk activity by Snk inhibitors has garnered significant attention in the field of molecular biology and discovery due to its implications in the modulation of various cellular functions.
Snk inhibitors are designed to interact with the active site of serine/threonine kinases, disrupting their catalytic activity. By inhibiting these enzymes, Snk inhibitors can interfere with downstream signaling pathways, ultimately influencing cellular behavior. Researchers have developed various Snk inhibitors with varying degrees of selectivity for different Snk enzymes, allowing for the precise manipulation of specific cellular processes. These inhibitors can be valuable tools in scientific research, enabling the investigation of kinase-dependent pathways and their roles in health and disease.
Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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BI 2536 | 755038-02-9 | sc-364431 sc-364431A | 5 mg 50 mg | $148.00 $515.00 | 8 | |
BI 2536 is a potent and selective inhibitor of PLKs, which can lead to cell cycle arrest and apoptosis by inhibiting PLK2 activity. | ||||||
GSK461364 | 929095-18-1 | sc-364504 sc-364504A | 10 mg 50 mg | $500.00 $1540.00 | ||
GSK461364 selectively targets PLK1 but also has inhibitory effects on PLK2, interfering with cell division and proliferation. | ||||||
ON-01910 | 1225497-78-8 | sc-364556 sc-364556A | 5 mg 10 mg | $300.00 $700.00 | ||
ON-01910 targets multiple kinases including PLK2, which can result in cell cycle disruption and antiproliferative effects. | ||||||
Purvalanol A | 212844-53-6 | sc-224244 sc-224244A | 1 mg 5 mg | $71.00 $291.00 | 4 | |
Purvalanol A is a cyclin-dependent kinase inhibitor that may also have inhibitory effects on PLK2, leading to cell cycle arrest. |