Date published: 2025-10-15

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Snk Inhibitors

Snk inhibitors are a class of chemical compounds that primarily target a specific group of enzymes known as serine/threonine kinases (Snk). Serine/threonine kinases are a vital component of cellular signaling pathways, playing a crucial role in the regulation of various cellular processes, including cell growth, proliferation, differentiation, and apoptosis. These enzymes are essential for maintaining cellular homeostasis and ensuring proper responses to external stimuli. The inhibition of Snk activity by Snk inhibitors has garnered significant attention in the field of molecular biology and discovery due to its implications in the modulation of various cellular functions.

Snk inhibitors are designed to interact with the active site of serine/threonine kinases, disrupting their catalytic activity. By inhibiting these enzymes, Snk inhibitors can interfere with downstream signaling pathways, ultimately influencing cellular behavior. Researchers have developed various Snk inhibitors with varying degrees of selectivity for different Snk enzymes, allowing for the precise manipulation of specific cellular processes. These inhibitors can be valuable tools in scientific research, enabling the investigation of kinase-dependent pathways and their roles in health and disease.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

BI 2536

755038-02-9sc-364431
sc-364431A
5 mg
50 mg
$148.00
$515.00
8
(1)

BI 2536 is a potent and selective inhibitor of PLKs, which can lead to cell cycle arrest and apoptosis by inhibiting PLK2 activity.

GSK461364

929095-18-1sc-364504
sc-364504A
10 mg
50 mg
$500.00
$1540.00
(0)

GSK461364 selectively targets PLK1 but also has inhibitory effects on PLK2, interfering with cell division and proliferation.

ON-01910

1225497-78-8sc-364556
sc-364556A
5 mg
10 mg
$300.00
$700.00
(0)

ON-01910 targets multiple kinases including PLK2, which can result in cell cycle disruption and antiproliferative effects.

Purvalanol A

212844-53-6sc-224244
sc-224244A
1 mg
5 mg
$71.00
$291.00
4
(2)

Purvalanol A is a cyclin-dependent kinase inhibitor that may also have inhibitory effects on PLK2, leading to cell cycle arrest.