Snk Activators refers to a class of chemical compounds that exhibit the unique capability to interact with and modulate the activity of the Snk protein. Snk, also known as Selenoprotein N kinase, is a protein that plays a role in cellular processes related to selenium metabolism and redox regulation. It is a member of the family of selenoproteins, which are characterized by the incorporation of the amino acid selenocysteine into their structure. Selenoproteins are essential for various cellular functions, including antioxidant defense and regulation of cellular redox status. Snk activators are compounds that can influence the activity of Snk, affecting selenium homeostasis and cellular responses to oxidative stress.
The mechanism of action of Snk activators typically involves their ability to modulate the phosphorylation or activity of the Snk protein. Snk is known to be involved in the regulation of selenoprotein synthesis and may also play a role in cellular responses to oxidative stress. Snk activators may interact with Snk directly, altering its enzymatic activity or substrate specificity. Alternatively, they may affect the cellular signaling pathways that regulate Snk, indirectly influencing its function. Understanding the properties and effects of Snk activators is significant in the context of selenium biology and cellular redox regulation, as it can provide insights into the intricate mechanisms that govern the maintenance of cellular oxidative balance and the synthesis of selenoproteins, which are critical for various physiological processes.
Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
---|---|---|---|---|---|---|
BI6727 | 755038-65-4 | sc-364432 sc-364432A sc-364432B sc-364432C sc-364432D | 5 mg 50 mg 100 mg 500 mg 1 g | $147.00 $1029.00 $1632.00 $3264.00 $4296.00 | 1 | |
BI 6727 selectively activates PLK2 through inhibition of ATP-binding, leading to cell cycle arrest. | ||||||
SC1 (Pluripotin) | 839707-37-8 | sc-255607 sc-255607A sc-255607B sc-255607C | 1 mg 5 mg 10 mg 25 mg | $164.00 $195.00 $464.00 $764.00 | ||
SC1 indirectly activates PLK2 by modulating pathways that upregulate PLK2 expression. | ||||||
Thymoquinone | 490-91-5 | sc-215986 sc-215986A | 1 g 5 g | $46.00 $130.00 | 21 | |
Thymoquinone can increase PLK2 activity through modulation of cellular signaling pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates PLK2 indirectly by increasing cAMP levels, which can enhance PLK2 expression. | ||||||
PD 0332991 Isethionate | 827022-33-3 | sc-478943 | 1 mg | $300.00 | ||
PD 0332991 upregulates PLK2 activity as part of its broader effects on cell cycle regulation. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Roscovitine enhances PLK2 activity by modulating cell cycle-related pathways. | ||||||
Dinaciclib | 779353-01-4 | sc-364483 sc-364483A | 5 mg 25 mg | $242.00 $871.00 | 1 | |
Dinaciclib can indirectly activate PLK2 by inhibiting competing kinases in the cell cycle pathway. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
ZM447439 activates PLK2 by affecting ATP-binding site dynamics. |