Date published: 2026-3-22

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SNAT4 Inhibitors

SNAT4 inhibitors are a class of chemical compounds designed to target and inhibit the activity of Sodium-coupled neutral amino acid transporter 4, also known as SNAT4. SNAT4 is a membrane protein that belongs to the solute carrier family and is primarily involved in the transport of neutral amino acids across cell membranes. These amino acids serve as essential building blocks for protein synthesis and are integral to various cellular processes, including cell growth and metabolism. SNAT4 is specifically responsible for the sodium-coupled transport of neutral amino acids, ensuring their uptake into cells. Inhibitors of SNAT4 are valuable tools for researchers interested in understanding the molecular mechanisms underlying amino acid transport and its impact on cellular physiology.

SNAT4 inhibitors are typically composed of small molecules or chemical compounds that are designed to interfere with the activity or interactions of SNAT4 within cellular pathways. By inhibiting SNAT4, these compounds can potentially block the sodium-coupled transport of neutral amino acids, leading to alterations in cellular amino acid uptake and availability. Researchers use SNAT4 inhibitors in laboratory settings to manipulate the activity of this transporter and study its roles in various biological contexts, such as protein synthesis, nutrient sensing, and cell signaling. These inhibitors provide valuable insights into the mechanisms governing amino acid transport across cell membranes, contributing to a deeper understanding of how cells acquire the essential nutrients required for their growth and function. While SNAT4 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricacies of SNAT4-mediated amino acid transport.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

This inhibits RNA polymerase II, potentially reducing the transcription of many genes, including those coding for transport proteins like SNAT4.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

By intercalating into DNA, it can inhibit RNA synthesis, potentially decreasing the expression of proteins such as SNAT4.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$97.00
$328.00
$676.00
$1467.00
6
(1)

Known to inhibit bacterial RNA polymerase; in eukaryotes, it may inhibit mitochondrial RNA polymerase, potentially affecting protein expression.

Puromycin

53-79-2sc-205821
sc-205821A
10 mg
25 mg
$166.00
$322.00
436
(1)

Causes premature chain termination during translation, which could non-specifically reduce the levels of many proteins, including SNAT4.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

While known as an antimalarial, it can affect endosomal acidification and possibly interfere with cellular processes regulating protein expression.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Disrupts protein transport by inhibiting the exchange of GDP to GTP, potentially affecting the expression and localization of proteins like SNAT4.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Activates adenylate cyclase and increases cAMP, which might modulate transcription factors and affect protein expression like SNAT4.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$58.00
$186.00
$94.00
21
(2)

Inhibits DNA topoisomerase I, leading to DNA damage and potentially altering gene expression profiles, including that of SNAT4.

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$66.00
$101.00
$143.00
85
(5)

Crosslinks DNA, which can inhibit DNA synthesis and could lead to reduced expression of various proteins, including SNAT4.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits eukaryotic protein synthesis, which could result in a general decrease in protein levels, including that of SNAT4.