Date published: 2026-1-30

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SMC CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. SMC gene silencers are available as SMC CRISPR/Cas9 Knockout plasmids and SMC Double Nickase Plasmids. SMC CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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SMC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMC1 CRISPR/Cas9 KO Plasmid (h)

sc-403715hGene KnockoutGFP0
(0)

SMC1 HDR Plasmid (h)

sc-403715-HDRhHomology Directed RepairPuromycin0
(0)

SMC1α CRISPR/Cas9 KO Plasmid (h)

sc-402865hGene KnockoutGFP0
(0)

SMC1α HDR Plasmid (h)

sc-402865-HDRhHomology Directed RepairPuromycin0
(0)

SMC2 Double Nickase Plasmid (h)

sc-411488-NIChGene KnockoutPuromycin0
(0)

SMC4 CRISPR/Cas9 KO Plasmid (h)

sc-405067hGene KnockoutGFP0
(0)

SMC4 HDR Plasmid (h)

sc-405067-HDRhHomology Directed RepairPuromycin0
(0)

SMC6 CRISPR/Cas9 KO Plasmid (h)

sc-402805hGene KnockoutGFP0
(0)

SMC6 HDR Plasmid (h)

sc-402805-HDRhHomology Directed RepairPuromycin0
(0)

SMC6 Double Nickase Plasmid (h)

sc-402805-NIChGene KnockoutPuromycin0
(0)

SMC6 Double Nickase Plasmid (h2)

sc-402805-NIC-2hGene KnockoutPuromycin0
(0)

SMC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMC1 CRISPR Activation Plasmid (h)

sc-403715-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC1α CRISPR Activation Plasmid (h)

sc-402865-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC1α CRISPR Activation Plasmid (h2)

sc-402865-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMC3 CRISPR Activation Plasmid (h)

sc-403950-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC4 CRISPR Activation Plasmid (h)

sc-405067-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC6 CRISPR Activation Plasmid (h)

sc-402805-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMC6 CRISPR Activation Plasmid (h2)

sc-402805-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)