Date published: 2025-10-11

1-800-457-3801

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Smad6 Antibodies

Santa Cruz Biotechnology delivers a wide array of Smad6 monoclonal antibodies for advanced research in cellular signaling pathways. Smad6 Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Smad6 is a critical intracellular mediator in the transforming growth factor-beta (TGF-β) signaling pathway, playing a vital role in regulating cellular responses to growth factors and cytokines. By inhibiting the transcriptional activity of Smad proteins, Smad6 helps maintain cellular homeostasis and prevent excessive signaling that could lead to pathological conditions. Understanding the function of Smad6 is essential for elucidating its role in development, immune response, and various diseases. Smad6 monoclonal antibodies enable researchers to investigate protein expression patterns across different cell types and tissues. Smad6 monoclonal antibodies support detailed analysis of protein-protein interactions and signaling cascades. Researchers can explore the molecular mechanisms underlying TGF-β pathway regulation with high specificity and reproducibility. Santa Cruz Biotechnology monoclonal antibodies for Smad6 contribute to advancing scientific understanding of cellular signaling and disease mechanisms.

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Smad6 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Smad6 Antibody (D-4)

sc-25321mouse IgG1 κ41-190 (h)WB, IP, ELISAm, r, h
9
(3)

Smad6 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad6 CRISPR/Cas9 KO Plasmid (h)

sc-401411hGene KnockoutGFP0
(0)

Smad6 HDR Plasmid (h)

sc-401411-HDRhHomology Directed RepairPuromycin0
(0)

Smad6 Double Nickase Plasmid (h)

sc-401411-NIChGene KnockoutPuromycin0
(0)

Smad6 Double Nickase Plasmid (h2)

sc-401411-NIC-2hGene KnockoutPuromycin0
(0)

Smad6 CRISPR/Cas9 KO Plasmid (m)

sc-421529mGene KnockoutGFP0
(0)

Smad6 Double Nickase Plasmid (m)

sc-421529-NICmGene KnockoutPuromycin0
(0)

Smad6 Double Nickase Plasmid (m2)

sc-421529-NIC-2mGene KnockoutPuromycin0
(0)

Smad6 CRISPR Activation Products

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Smad6 CRISPR Activation Plasmid (h)

sc-401411-ACThGene ActivationPuro, Blast, Hygro0
(0)

Smad6 CRISPR Activation Plasmid (h2)

sc-401411-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Smad6 Lentiviral Activation Particles (h)

sc-401411-LAChGene ActivationPuro, Blast, Hygro0
(0)

Smad6 Lentiviral Activation Particles (h2)

sc-401411-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Smad6 CRISPR Activation Plasmid (m)

sc-421529-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Smad6 CRISPR Activation Plasmid (m2)

sc-421529-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Smad6 Lentiviral Activation Particles (m)

sc-421529-LACmGene ActivationPuro, Blast, Hygro0
(0)

Smad6 Lentiviral Activation Particles (m2)

sc-421529-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Smad6 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad6 siRNA (h)

sc-38380hGene SilencingN/A
4
(1)

Smad6 shRNA Plasmid (h)

sc-38380-SHhGene SilencingPuromycin
4
(1)

Smad6 shRNA (h) Lentiviral Particles

sc-38380-VhGene SilencingPuromycin
4
(1)

Smad6 siRNA (m)

sc-38381mGene SilencingN/A
4
(0)

Smad6 shRNA Plasmid (m)

sc-38381-SHmGene SilencingPuromycin
4
(0)

Smad6 shRNA (m) Lentiviral Particles

sc-38381-VmGene SilencingPuromycin
4
(0)