Slp5 Activators
Synaptotagmin-like protein 5 (Slp5) belongs to the synaptotagmin family, which is known for its involvement in the regulation of membrane trafficking and neurotransmitter release. Members of this family typically contain C2 domains that bind to calcium and phospholipids, which are key in their role in vesicle trafficking and exocytosis.As a "like" member of the synaptotagmin family, Slp5 shares homology with classical synaptotagmins but can have distinct functions or regulatory mechanisms. These proteins are often involved in the fine-tuning of vesicle-mediated transport and membrane fusion events, which are critical for processes such as synaptic transmission, hormone release, and other cellular secretion mechanisms.
The specific function of Slp5 can vary by cell type and organism. In general, synaptotagmin-like proteins are thought to help coordinate the docking and release of vesicles in response to increases in intracellular calcium levels, a crucial step in ensuring rapid and precise signal transmission across synapses or release of substances from a cell. These proteins can interact with SNARE proteins and other components of the vesicle fusion machinery, modulating their function in a calcium-dependent manner.Mutations or dysregulation of synaptotagmin-like proteins, including Slp5, could potentially lead to various neurological disorders or contribute to the pathology of metabolic diseases, as vesicle trafficking is critical in many signaling pathways and cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates Protein Kinase C (PKC), which can influence synaptic vesicle exocytosis, potentially affecting SYTL5-related pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which may indirectly modulate SYTL5 activity through PKA-dependent pathways. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
This compound disrupts the Golgi apparatus and could affect the trafficking of proteins like SYTL5. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubules and can influence intracellular trafficking, potentially impacting SYTL5 function. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin is an ionophore that disrupts intracellular ion gradients, potentially affecting SYTL5-related vesicle trafficking. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
An inhibitor of PI3K, wortmannin may indirectly affect SYTL5 by altering intracellular signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
This is another PI3K inhibitor, which could impact signaling pathways related to SYTL5 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
As an mTOR inhibitor, rapamycin may affect various cellular processes, potentially influencing SYTL5 function. | ||||||
Benzyl mercaptan | 100-53-8 | sc-353053 sc-353053A | 25 g 100 g | $41.00 $63.00 | ||
While a biological material, NGF's role in neural development and function may indirectly influence SYTL5. | ||||||
Bis(pinacolato)diboron | 73183-34-3 | sc-252467 sc-252467A | 1 g 5 g | $43.00 $80.00 | ||
Similar to NGF, PDGF is a biological factor that can modulate cellular signaling pathways affecting SYTL5. | ||||||