Slfn3 Activators
Slfn3 Activators encompass a group of chemical compounds that can enhance the functional activity of Slfn3, a protein involved in the regulation of cell growth and differentiation. Slfn3 Activators are a class of chemicals that modulate the functional activity of the Slfn3 protein, enhancing its regulatory effects within cellular processes.
Direct Slfn3 Activators interact with the Slfn3 protein at specific sites that are crucial for its regulatory function. These activators can effectively increase the protein's ability to modulate its target cellular processes, perhaps influencing cell cycle progression or the response to immunological stimuli. The mechanism of direct activation could involve a conformational change in Slfn3 induced by the binding of the activator, which could result in an increased affinity of Slfn3 for its substrates or interacting partners within the cell. This could also include facilitating the localization of Slfn3 to sites within the cell where it exerts its effects, or even stabilizing the protein to prolong its active state. Indirect Slfn3 Activators, in contrast, would not bind to Slfn3 directly but would work by modulating the cellular environment or signaling pathways that influence the activity of Slfn3. This could include chemicals that enhance the expression of the Slfn3 gene, increasing the production and availability of the protein in the cell. Alternatively, indirect activators might work by inhibiting the degradation of Slfn3, thereby increasing its stability and duration of action. Furthermore, these activators could trigger post-translational modifications of Slfn3 that affect its activity, such as phosphorylation, which might alter its regulatory functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Rosiglitazone is a PPARγ agonist. PPARγ activation can regulate the expression of Slfn3, enhancing its functional activity. The PPARγ pathway is known to control the expression of a series of genes involved in metabolism and inflammation, including Slfn3. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a glucocorticoid receptor (GR) agonist. Activation of the GR can lead to the upregulation of Slfn3. Slfn3 is one of the genes that can be regulated by GRs, which are involved in the control of genes related to immune response and metabolism. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin is an activator of adenylyl cyclase, which increases cyclic AMP (cAMP) levels. Elevated cAMP can stimulate the PKA pathway, leading to enhanced Slfn3 activity. Slfn3 is known to be responsive to changes in cAMP levels. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram is a PDE4 inhibitor that increases cAMP levels. Increased cAMP can stimulate the PKA pathway, which is known to enhance Slfn3 activity. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin can activate the PI3K/AKT pathway, which is known to enhance Slfn3 activity. Slfn3 is responsive to changes in the cellular energy state, which can be regulated by insulin. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
Metformin indirectly activates AMPK, which can enhance Slfn3 activity. Slfn3 is known to be responsive to changes in cellular energy levels, which can be regulated by AMPK. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR is an activator of AMPK. AMPK activation can enhance the functional activity of Slfn3 as it responds to changes in cellular energy levels. | ||||||
Troglitazone | 97322-87-7 | sc-200904 sc-200904B sc-200904A | 5 mg 10 mg 25 mg | $108.00 $200.00 $426.00 | 9 | |
Troglitazone is a PPARγ agonist. Activation of PPARγ can enhance Slfn3 activity by regulating its expression. PPARγ is known to control the expression of a series of genes involved in metabolism and inflammation, including Slfn3. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Pioglitazone is another PPARγ agonist that can enhance Slfn3 activity by regulating its expression. PPARγ is known to control the expression of a series of genes involved in metabolism and inflammation, including Slfn3. | ||||||
WY 14643 | 50892-23-4 | sc-203314 | 50 mg | $133.00 | 7 | |
WY-14643 is a PPARα agonist. PPARα activation can regulate the expression of Slfn3, enhancing its functional activity. The PPARα pathway is known to control the expression of a series of genes involved in metabolism and inflammation, including Slfn3. | ||||||