Slac2-a Inhibitors
Slac2-a Inhibitors belong to a distinct chemical class that has garnered significant attention in the field of molecular biology and cellular physiology. These compounds are characterized by their ability to selectively target and inhibit Slac2-a, a protein of paramount importance in various cellular processes. Slac2-a, also known as Synaptotagmin-like protein 4 (Syt4), is primarily found in synaptic vesicles and plays a crucial role in the regulation of neurotransmitter release. It acts as a calcium sensor and is involved in the exocytosis of neurotransmitters, making it a pivotal player in the intricate machinery of synaptic transmission.
Slac2-a Inhibitors involves their capacity to interfere with the binding of calcium ions to Slac2-a. By doing so, these inhibitors hinder the fusion of synaptic vesicles with the cell membrane, thereby impeding the release of neurotransmitters into the synaptic cleft. This disruption in neurotransmitter release can have profound effects on neuronal communication and synaptic plasticity. Slac2-a Inhibitors have become indispensable tools in neurobiological research, enabling scientists to dissect the intricate processes underlying neurotransmission and synaptic function.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Roscovitine is a purine analog that inhibits cyclin-dependent kinases (CDKs), which can indirectly affect MLPH function by altering the cell cycle and potentially disrupting intracellular trafficking processes where MLPH is involved. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and can disrupt the normal microtubule dynamics necessary for melanosome transport, where MLPH plays a crucial role. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole is a microtubule-depolymerizing agent that can disrupt the microtubule network, thereby indirectly affecting MLPH-involved melanosome transport. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin and inhibits its polymerization into microtubules, indirectly affecting MLPH function by disrupting microtubule-dependent processes. | ||||||
Monastrol | 254753-54-3 | sc-202710 sc-202710A | 1 mg 5 mg | $120.00 $233.00 | 10 | |
Monastrol is a kinesin Eg5 inhibitor that disrupts the bipolar spindle formation, indirectly affecting the cellular transport mechanisms where MLPH is involved. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
ML-7 is an inhibitor of myosin light chain kinase (MLCK), which can affect cytoskeletal dynamics and influence the intracellular transport pathways involving MLPH. | ||||||
Gö 6976 | 136194-77-9 | sc-221684 | 500 µg | $223.00 | 8 | |
Go6976 is a protein kinase C inhibitor that can modulate signal transduction pathways, indirectly affecting the transport and localization functions of MLPH. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $180.00 $299.00 | 59 | |
Jasplakinolide is an actin polymerization inducer that can disrupt actin dynamics, indirectly influencing MLPH-associated melanosome transport. | ||||||
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $127.00 $572.00 $4090.00 $20104.00 | 20 | |
Withaferin A is an inhibitor of vimentin, a component of the cytoskeleton, which can disrupt intermediate filament organization and potentially affect MLPH-related transport processes. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Latrunculin A is an actin polymerization inhibitor that disrupts actin filaments, indirectly affecting the intracellular transport mechanisms where MLPH operates. | ||||||