Date published: 2025-12-14

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Shc Antibodies

Santa Cruz Biotechnology features a diverse variety of Shc monoclonal antibodies for various research applications. Shc monoclonal antibodies are effective tools for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Shc proteins function as key mediators in signal transduction pathways, particularly in growth factor receptor signaling. Shc signaling molecules actively participate in cellular processes including proliferation, differentiation, and survival. Understanding Shc protein functions is crucial for investigating various physiological and pathological conditions. Research focusing on Shc proteins reveals important insights into cancer biology and diseases involving disrupted signaling pathways. Shc monoclonal antibodies enable detailed examination of protein interactions and cellular mechanisms. The high-quality Shc monoclonal antibodies from Santa Cruz Biotechnology support researchers worldwide in advancing scientific understanding of cellular signaling pathways and disease mechanisms.

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Shc Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

N-Shc Antibody (H-7)

sc-365598mouse IgG1 κ191-330 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(3)

N-Shc Antibody (23)

sc-135996mouse IgG1239-374 (m)WB, IP, IFm, r, h

new

(2)

Shc Antibody (PG-797)

sc-967mouse IgG1 κ476-583 (h)WB, IP, IF, IHC(P), FCMm, r, h
81
(15)

Shc Antibody (B-9)

sc-393717mouse IgG2b κ554-585 (h)WB, IP, IF, ELISAm, r, h
1
(1)

Shc Antibody (F-7)

sc-398163mouse IgG1 κ366-473 (h)WB, IP, IF, ELISAm, r, h

new

(1)

Shc Antibody (H-11)

sc-398289mouse IgG2a κ366-473 (h)WB, IP, IF, ELISAm, r, h
1
(1)

Phospho-Specific Shc Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-Shc Antibody (6E10)

sc-81520mouse IgG1Ser 36 (h)WBm, r, h and canine
5
(1)

p-Shc Antibody (1E3)

sc-81519mouse IgG1Tyr 239/240 (h)WB, IPm, r, h and canine

new

(1)

p-Shc Antibody (15E11)

sc-81518mouse IgG1Tyr 317 (h)WB, IP, IFm, r, h and canine

new

(2)

p-Shc Antibody (73.Tyr 349/350)

sc-293148mouse IgG1 κTyr 349/Tyr 350 (h)WB, IP, ELISAm, r, h

new

(2)

Shc CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

N-Shc CRISPR/Cas9 KO Plasmid (h)

sc-401571hGene KnockoutGFP0
(0)

N-Shc HDR Plasmid (h)

sc-401571-HDRhHomology Directed RepairPuromycin0
(0)

N-Shc Double Nickase Plasmid (h)

sc-401571-NIChGene KnockoutPuromycin0
(0)

N-Shc Double Nickase Plasmid (h2)

sc-401571-NIC-2hGene KnockoutPuromycin0
(0)

N-Shc CRISPR/Cas9 KO Plasmid (m)

sc-422922mGene KnockoutGFP0
(0)

N-Shc HDR Plasmid (m)

sc-422922-HDRmHomology Directed RepairPuromycin0
(0)

N-Shc Double Nickase Plasmid (m)

sc-422922-NICmGene KnockoutPuromycin0
(0)

N-Shc Double Nickase Plasmid (m2)

sc-422922-NIC-2mGene KnockoutPuromycin0
(0)

Shc CRISPR/Cas9 KO Plasmid (h)

sc-400914hGene KnockoutGFP0
(0)

Shc HDR Plasmid (h)

sc-400914-HDRhHomology Directed RepairPuromycin0
(0)

Shc Double Nickase Plasmid (h)

sc-400914-NIChGene KnockoutPuromycin0
(0)

Shc Double Nickase Plasmid (h2)

sc-400914-NIC-2hGene KnockoutPuromycin0
(0)

Shc CRISPR/Cas9 KO Plasmid (m)

sc-422921mGene KnockoutGFP0
(0)

Shc HDR Plasmid (m)

sc-422921-HDRmHomology Directed RepairPuromycin0
(0)

Shc Double Nickase Plasmid (m)

sc-422921-NICmGene KnockoutPuromycin0
(0)

Shc Double Nickase Plasmid (m2)

sc-422921-NIC-2mGene KnockoutPuromycin0
(0)

SHC4 CRISPR/Cas9 KO Plasmid (h)

sc-409451hGene KnockoutGFP0
(0)

SHC4 HDR Plasmid (h)

sc-409451-HDRhHomology Directed RepairPuromycin0
(0)

SHC4 Double Nickase Plasmid (h)

sc-409451-NIChGene KnockoutPuromycin0
(0)

SHC4 Double Nickase Plasmid (h2)

sc-409451-NIC-2hGene KnockoutPuromycin0
(0)

Shc4 CRISPR/Cas9 KO Plasmid (m)

sc-435455mGene KnockoutGFP0
(0)

Shc4 HDR Plasmid (m)

sc-435455-HDRmHomology Directed RepairPuromycin0
(0)

Shc4 Double Nickase Plasmid (m)

sc-435455-NICmGene KnockoutPuromycin0
(0)

Shc4 Double Nickase Plasmid (m2)

sc-435455-NIC-2mGene KnockoutPuromycin0
(0)

Shc CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

N-Shc CRISPR Activation Plasmid (h)

sc-401571-ACThGene ActivationPuro, Blast, Hygro0
(0)

N-Shc CRISPR Activation Plasmid (h2)

sc-401571-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

N-Shc Lentiviral Activation Particles (h)

sc-401571-LAChGene ActivationPuro, Blast, Hygro0
(0)

N-Shc Lentiviral Activation Particles (h2)

sc-401571-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

N-Shc CRISPR Activation Plasmid (m)

sc-422922-ACTmGene ActivationPuro, Blast, Hygro0
(0)

N-Shc CRISPR Activation Plasmid (m2)

sc-422922-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

N-Shc Lentiviral Activation Particles (m)

sc-422922-LACmGene ActivationPuro, Blast, Hygro0
(0)

N-Shc Lentiviral Activation Particles (m2)

sc-422922-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Shc CRISPR Activation Plasmid (h)

sc-400914-ACThGene ActivationPuro, Blast, Hygro0
(0)

Shc CRISPR Activation Plasmid (h2)

sc-400914-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Shc Lentiviral Activation Particles (h)

sc-400914-LAChGene ActivationPuro, Blast, Hygro0
(0)

Shc Lentiviral Activation Particles (h2)

sc-400914-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Shc CRISPR Activation Plasmid (m)

sc-422921-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Shc CRISPR Activation Plasmid (m2)

sc-422921-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Shc Lentiviral Activation Particles (m)

sc-422921-LACmGene ActivationPuro, Blast, Hygro0
(0)

Shc Lentiviral Activation Particles (m2)

sc-422921-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SHC4 CRISPR Activation Plasmid (h)

sc-409451-ACThGene ActivationPuro, Blast, Hygro0
(0)

SHC4 CRISPR Activation Plasmid (h2)

sc-409451-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SHC4 Lentiviral Activation Particles (h)

sc-409451-LAChGene ActivationPuro, Blast, Hygro0
(0)

SHC4 Lentiviral Activation Particles (h2)

sc-409451-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Shc4 CRISPR Activation Plasmid (m)

sc-435455-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Shc4 CRISPR Activation Plasmid (m2)

sc-435455-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Shc4 Lentiviral Activation Particles (m)

sc-435455-LACmGene ActivationPuro, Blast, Hygro0
(0)

Shc4 Lentiviral Activation Particles (m2)

sc-435455-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Shc siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

N-Shc siRNA (h)

sc-40975hGene SilencingN/A0
(0)

N-Shc shRNA Plasmid (h)

sc-40975-SHhGene SilencingPuromycin0
(0)

N-Shc shRNA (h) Lentiviral Particles

sc-40975-VhGene SilencingPuromycin0
(0)

N-Shc siRNA (m)

sc-40976mGene SilencingN/A0
(0)

N-Shc shRNA Plasmid (m)

sc-40976-SHmGene SilencingPuromycin0
(0)

N-Shc shRNA (m) Lentiviral Particles

sc-40976-VmGene SilencingPuromycin0
(0)

Shc siRNA (h)

sc-29480hGene SilencingN/A
7
(0)

Shc shRNA Plasmid (h)

sc-29480-SHhGene SilencingPuromycin
7
(0)

Shc shRNA (h) Lentiviral Particles

sc-29480-VhGene SilencingPuromycin
7
(0)

Shc siRNA (m)

sc-29481mGene SilencingN/A0
(0)

Shc shRNA Plasmid (m)

sc-29481-SHmGene SilencingPuromycin0
(0)

Shc shRNA (m) Lentiviral Particles

sc-29481-VmGene SilencingPuromycin0
(0)

Shc4 siRNA (h)

sc-90080hGene SilencingN/A0
(0)

Shc4 shRNA Plasmid (h)

sc-90080-SHhGene SilencingPuromycin0
(0)

Shc4 shRNA (h) Lentiviral Particles

sc-90080-VhGene SilencingPuromycin0
(0)

Shc4 siRNA (m)

sc-153445mGene SilencingN/A0
(0)

Shc4 shRNA Plasmid (m)

sc-153445-SHmGene SilencingPuromycin0
(0)

Shc4 shRNA (m) Lentiviral Particles

sc-153445-VmGene SilencingPuromycin0
(0)

Shc Proteins

Empty Table HeaderProduct NameCATALOG #AmountSpeciesCitationsRATING

Shc-SH2 (366-473)

sc-4110 WB10 µg/0.1 mlh0
(0)