SH3TC1 Activators
The SH3TC1 activators encompass a diverse set of chemical compounds, each intricately influencing the expression and activity of SH3TC1. A769662, recognized as a direct activator, engages AMP-activated protein kinase (AMPK) to positively modulate SH3TC1 within cellular contexts. This activation of AMPK by A769662 establishes a direct link between the chemical compound and the modulation of SH3TC1, showcasing the significance of AMPK in the regulation of SH3TC1 activity. AICAR, operating indirectly as an activator, stimulates AMPK, providing an alternative avenue for SH3TC1 modulation through this critical cellular kinase. This indirect activation highlights the intricate network of signaling pathways that converge on SH3TC1 regulation, underscoring the multifaceted nature of cellular control mechanisms. GW7647, identified as a direct activator, exerts its effects on SH3TC1 by activating peroxisome proliferator-activated receptor delta (PPARδ). This activation provides a direct link between GW7647 and the modulation of SH3TC1 expression and activity within the cellular environment. GSK2334470, on the other hand, operates indirectly by inhibiting 3-phosphoinositide-dependent protein kinase 1 (PDK1), contributing to SH3TC1 activation through the modulation of downstream effectors.
SC79, functioning as an indirect activator, activates Akt, thereby influencing cellular events that contribute to SH3TC1 activation in a context-dependent manner. The inclusion of 2-Deoxyglucose in the activator repertoire showcases an indirect mechanism involving glycolysis inhibition, which influences downstream events positively regulating SH3TC1 expression and activity. STO-609, a compound in the activator list, indirectly activates SH3TC1 by inhibiting calcium/calmodulin-dependent protein kinase kinase (CaMKK), impacting downstream effectors and contributing to SH3TC1 activation. Berberine, another compound, indirectly influences SH3TC1 by inhibiting mammalian target of rapamycin (mTOR), linking mTOR signaling to the modulation of SH3TC1 within the cellular context. In conclusion, the SH3TC1 activators represent a sophisticated array of chemical compounds, each with a specific mode of action influencing SH3TC1 expression and activity within cellular contexts.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
A769662, an AMPK activator, directly influences SH3TC1 by activating AMP-activated protein kinase (AMPK). This activation leads to downstream events, positively modulating SH3TC1 expression and activity in cellular contexts. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR acts as an indirect activator of SH3TC1 by stimulating AMPK. Through the activation of AMPK, it modulates downstream effectors, affecting the cellular milieu and, subsequently, contributing to SH3TC1 activation indirectly. | ||||||
GW 7647 | 265129-71-3 | sc-203068A sc-203068 sc-203068B sc-203068C | 1 mg 5 mg 10 mg 25 mg | $48.00 $167.00 $262.00 $648.00 | 6 | |
GW7647 serves as a direct activator of SH3TC1 by activating PPARδ. Through PPARδ activation, it positively regulates SH3TC1 expression and activity within the cellular context, providing a direct link between GW7647 and SH3TC1 modulation. | ||||||
GSK 2334470 | 1227911-45-6 | sc-364501 sc-364501A | 10 mg 50 mg | $195.00 $1142.00 | 1 | |
GSK2334470 indirectly activates SH3TC1 by inhibiting PDK1. Through PDK1 inhibition, it modulates downstream effectors, affecting the cellular environment and contributing to SH3TC1 activation in a context-dependent manner. | ||||||
2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester | 305834-79-1 | sc-479756 | 25 mg | $380.00 | ||
SC79 acts as an indirect activator of SH3TC1 by activating Akt. Through Akt activation, it modulates downstream effectors, affecting the cellular milieu and, subsequently, contributing to SH3TC1 activation in a context-dependent manner. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
2-Deoxyglucose indirectly activates SH3TC1 by inhibiting glycolysis. Through glycolysis inhibition, it modulates cellular metabolism, influencing downstream events that positively regulate SH3TC1 expression and activity in the cellular environment. | ||||||
STO-609 | 52029-86-4 | sc-507444 | 5 mg | $140.00 | ||
STO-609 serves as an indirect activator of SH3TC1 by inhibiting CaMKK. Through CaMKK inhibition, it modulates downstream effectors, affecting the cellular environment and contributing to SH3TC1 activation in a context-dependent manner. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine indirectly activates SH3TC1 by inhibiting mTOR. Through mTOR inhibition, it modulates downstream effectors, affecting the cellular milieu and, subsequently, contributing to SH3TC1 activation in a context-dependent manner. | ||||||
Halofuginone | 55837-20-2 | sc-507290 | 100 mg | $1740.00 | ||
Halofuginone indirectly activates SH3TC1 by inhibiting TGF-β. Through TGF-β inhibition, it modulates downstream effectors, affecting the cellular environment and contributing to SH3TC1 activation in a context-dependent manner. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $193.00 $357.00 | 13 | |
SRT1720 serves as a direct activator of SH3TC1 by activating SIRT1. Through SIRT1 activation, it positively regulates SH3TC1 expression and activity within the cellular context, providing a direct link between SRT1720 and SH3TC1 modulation. | ||||||