SEZ6 Activators
SEZ6, or Seizure related 6 homolog, is a protein of interest within the neuroscience community due to its association with neurological development and function. Encoded by the SEZ6 gene, this protein is believed to influence processes such as neuronal growth, synaptic plasticity, and cell adhesion, factors integral to the proper wiring and function of the nervous system.SEZ6 is characterized as a type I transmembrane protein that contains several CUB domains and one SEA domain, which are often found in proteins involved in cell adhesion and the immune response. Its exact molecular functions are not fully elucidated, but the presence of these domains suggests a role in intercellular interactions and possibly in the modulation of synapse formation and maintenance.
Mutations in the SEZ6 gene have been linked to neurological conditions, including autism spectrum disorders and seizures, indicating its importance in brain health and disease. Research on SEZ6 also points to involvement in neurodegenerative diseases, such as Alzheimer's disease, where synaptic dysfunction is a key feature.SEZ6's role in the brain is complex and multifaceted. It is thought to interact with various intracellular signaling pathways that govern neuronal differentiation and maturation. As a result, SEZ6 is not only a crucial protein for normal cognitive development but also a promising target for research into therapies for a range of neurological disorders.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises intracellular cAMP, which may enhance neural gene expression, including SEZ6. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium affects neural processes and may influence genes like SEZ6 involved in synaptic function. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid modulates gene expression through histone deacetylase inhibition, affecting neural genes. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine affects DNA methylation, potentially leading to increased SEZ6 expression in neurons. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
β-estradiol interacts with estrogen receptors, which may regulate genes like SEZ6 in the brain. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A, as an HDAC inhibitor, could affect the chromatin of genes like SEZ6, altering expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate is another HDAC inhibitor that may enhance expression of genes involved in neurodevelopment. | ||||||
K-252a | 99533-80-9 | sc-200517 sc-200517B sc-200517A | 100 µg 500 µg 1 mg | $129.00 $214.00 $498.00 | 19 | |
K252a modulates kinase activity, which may influence signaling pathways regulating SEZ6 expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 inhibits MEK, potentially affecting transcription factors that regulate SEZ6 expression. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB431542 inhibits TGF-β signaling, which could modify expression patterns of neural proteins like SEZ6. | ||||||