SETD4 Inhibitors
SETD4 inhibitors, in a broad sense, consist of chemicals that can influence the process of methylation, especially the methylation of histones, a process where SETD4 is likely to play a role. 5'-Deoxy-5'-Methylthioadenosine, Chaetocin, BIX-01294, Methylthioadenosine, RG108, Sinefungin, Amodiaquine, and others all function as inhibitors of various methyltransferases. By inhibiting these enzymes, these chemicals can potentially affect the function of SETD4.
On the other hand, Adenosine-2',3'-dialdehyde, 3-Deazaneplanocin A, DZNep, all inhibit S-adenosylhomocysteine hydrolase, an enzyme that regulates the cellular concentration of S-adenosylmethionine, a universal methyl group donor. By inhibiting S-adenosylhomocysteine hydrolase, these chemicals can influence the function of SETD4.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5′-Deoxy-5′-methylthioadenosine | 2457-80-9 | sc-202427 | 50 mg | $122.00 | 1 | |
This compound is a known inhibitor of methyltransferases and can potentially inhibit SETD4. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $126.00 | 5 | |
Chaetocin is a known inhibitor of various histone methyltransferases and can potentially inhibit SETD4. | ||||||
Adenosine, periodate oxidized | 34240-05-6 | sc-214510 sc-214510A | 25 mg 100 mg | $119.00 $364.00 | ||
This compound is a known inhibitor of S-adenosylhomocysteine hydrolase, an enzyme relevant to methyltransferase reactions, and can potentially influence SETD4 activity. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $37.00 $112.00 $408.00 | ||
BIX-01294 is a histone methyltransferase inhibitor that can potentially inhibit SETD4. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
RG108 is a non-nucleoside inhibitor of DNA methyltransferases, and can potentially inhibit SETD4. | ||||||
Sinefungin | 58944-73-3 | sc-203263 sc-203263B sc-203263C sc-203263A | 1 mg 100 mg 1 g 10 mg | $271.00 $5202.00 $40368.00 $704.00 | 4 | |
Sinefungin is a universal methyltransferase inhibitor that can potentially inhibit SETD4. | ||||||
3-Deazaneplanocin, HCl salt | 120964-45-6 | sc-351856 sc-351856A sc-351856B | 1 mg 5 mg 10 mg | $256.00 $612.00 $936.00 | 2 | |
3-Deazaneplanocin is an inhibitor of S-adenosylhomocysteine hydrolase and can potentially influence SETD4 activity. | ||||||
Procainamide hydrochloride | 614-39-1 | sc-202297 | 10 g | $53.00 | ||
Procainamide is a DNA methyltransferase inhibitor and can potentially inhibit SETD4. | ||||||
Amodiaquine | 86-42-0 | sc-207282 | 10 mg | $342.00 | 1 | |
Amodiaquine is a histone methyltransferase inhibitor that can potentially inhibit SETD4. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is a known inhibitor of protein synthesis and can potentially influence SETD4 activity. | ||||||