Date published: 2026-5-16

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Adenosine, periodate oxidized (CAS 34240-05-6)

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Alternate Names:
ADOX; Adenosine-2′,3′-dialdehyde
Application:
Adenosine, periodate oxidized is an inhibitor of S-adenosylhomocysteine hydrolase
CAS Number:
34240-05-6
Purity:
≥93%
Molecular Weight:
265.23
Molecular Formula:
C10H11N5O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Adenosine, periodate oxidized, also known as Adenosine dialdehyde (ADA), is a derivative of adenosine, a nucleoside present in all living cells and pivotal for cellular energy metabolism, Adenosine, periodate oxidized holds promise for diverse applications. Its reactivity and synthesis methods have been extensively explored. In scientific research, Adenosine, periodate oxidized finds utility in multiple domains. Through selective modification of amino acid residues in proteins, Adenosine, periodate oxidized enables the exploration of specific residue roles in protein function. Moreover, its inhibition of enzymes containing targeted amino acid residues facilitates the study of enzyme kinetics. The involvement of adenosine in cellular signaling pathways, such as the adenosine receptor signaling pathway, can also be elucidated using Adenosine, periodate oxidized. The reactivity of Adenosine, periodate oxidized arises from its capacity to react with amino acid residues, including lysine, arginine, and histidine, within proteins. These reactions generate stable adducts, enabling the investigation of individual residue contributions to protein function. Adenosine, periodate oxidized′s high reactivity can be attributed to the presence of two aldehyde groups, facilitating nucleophilic reactions with amino acids. Overall, Adenosine, periodate oxidized stands as a versatile compound. Its reactivity and specific interactions with proteins and amino acids allows insights into intricate biological processes.


Adenosine, periodate oxidized (CAS 34240-05-6) References

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  2. Expression and function of methylthioadenosine phosphorylase in chronic liver disease.  |  Czech, B., et al. 2013. PLoS One. 8: e80703. PMID: 24324622
  3. Protein arginine methyltransferase 6 enhances ligand-dependent and -independent activity of estrogen receptor α via distinct mechanisms.  |  Sun, Y., et al. 2014. Biochim Biophys Acta. 1843: 2067-78. PMID: 24742914
  4. KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5.  |  di Caprio, R., et al. 2015. Biology (Basel). 4: 41-9. PMID: 25585209
  5. Characterization of adenosine-bovine serum albumin immunogen and its antibodies.  |  Ali, MA. and Jacob, TM. 1985. Immunol Invest. 14: 85-94. PMID: 2581895
  6. Role of S-adenosylhomocysteine in cardiovascular disease and its potential epigenetic mechanism.  |  Xiao, Y., et al. 2015. Int J Biochem Cell Biol. 67: 158-66. PMID: 26117455
  7. Ablation of Myeloid ADK (Adenosine Kinase) Epigenetically Suppresses Atherosclerosis in ApoE-/- (Apolipoprotein E Deficient) Mice.  |  Zhang, M., et al. 2018. Arterioscler Thromb Vasc Biol. 38: 2780-2792. PMID: 30571174
  8. Arginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells.  |  Liu, X., et al. 2021. Nat Commun. 12: 3780. PMID: 34145242
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Adenosine, periodate oxidized, 25 mg

sc-214510
25 mg
$119.00

Adenosine, periodate oxidized, 100 mg

sc-214510A
100 mg
$364.00