Procainamide hydrochloride CAS: 614-39-1
MF: C13H21N3O HCl
MW: 271.8
A Na+ channel blocker and Dnmt inhibitor.

Procainamide hydrochloride (CAS 614-39-1)

Procainamide hydrochloride | CAS 614-39-1 is rated 5.0 out of 5 by 1.
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Synonym: 4-Amino-N-[2'-(diethylamino)ethyl]benzamide hydrochloride
Application: A Na+ channel blocker and Dnmt inhibitor
CAS Number: 614-39-1
Purity: ≥98%
Molecular Weight: 271.8
Molecular Formula: C13H21N3O HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Procainamide hydrochloride is the hydrochloride salt preparation of Procainamide, a potent blocker of Na+ channels. Procainamide demonstrates antiarrhythmic effects correlated with blockade of the Na+ channels. Procainamide hydrochloride is an inhibitor of DNA methyltransferase (Dnmt).


References

1. Roden, D.M., et al. 1983. Pharmacol. Ther. 23: 179-191. PMID: 6199801
2. Sheldon, R.S., et al. 1987. Circ. Res. 61: 492-497. PMID: 2443266
3. Atkinson, A.J., et al. 1988. Angiology. 39: 655-667. PMID: 2457345

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml), ethanol, chloroform, and methanol. Insoluble in ethyl acetate.
Storage :
Store at room temperature
Melting Point :
167-169° C (lit.)
Boiling Point :
421.8° C at 760 mmHg (Predicted)
Refractive Index :
n20D ~1.55 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
CV2295000
PubChem CID :
66068
Merck Index :
14: 7756
MDL Number :
MFCD00012998
EC Number :
210-381-7
Beilstein Registry :
3729517
SMILES :
CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Atkinson et al Atkinson et al. (PubMed ID 2457345) showed that Procainamide hydrochloride prolonged action potential duration more than the PA metabolite, N-acetylprocainamide, in patients with arrhythmias. -SCBT Publication Review
Date published: 2015-02-11
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