Procainamide hydrochloride is the hydrochloride salt preparation of Procainamide, a potent blocker of Na+ channels. Procainamide demonstrates antiarrhythmic effects correlated with blockade of the Na+ channels. Procainamide hydrochloride is an inhibitor of DNA methyltransferase (Dnmt).
Soluble in water (50 mg/ml), ethanol, chloroform, and methanol. Insoluble in ethyl acetate.
Store at room temperature
167-169° C (lit.)
421.8° C at 760 mmHg (Predicted)
n20D ~1.55 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Certificate of Analysis
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Rated 5 out of
Atkinson et alAtkinson et al. (PubMed ID 2457345) showed that Procainamide hydrochloride prolonged action potential duration more than the PA metabolite, N-acetylprocainamide, in patients with arrhythmias. -SCBT Publication Review
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