Date published: 2026-7-9

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Sec CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. Sec gene silencers are available as Sec CRISPR/Cas9 Knockout plasmids and Sec Double Nickase Plasmids. Sec CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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Sec CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Sec61α2 CRISPR/Cas9 KO Plasmid (h)

sc-402223Gene Knockouth0
(0)

Sec6 CRISPR/Cas9 KO Plasmid (h)

sc-405053Gene Knockouth0
(0)

Sec15A CRISPR/Cas9 KO Plasmid (h)

sc-405860Gene Knockouth0
(0)

Sec10 CRISPR/Cas9 KO Plasmid (h)

sc-406954Gene Knockouth0
(0)

Sec62 CRISPR/Cas9 KO Plasmid (h)

sc-407292Gene Knockouth0
(0)

Sec15B CRISPR/Cas9 KO Plasmid (h)

sc-407519Gene Knockouth0
(0)

Sec63 CRISPR/Cas9 KO Plasmid (h)

sc-407766Gene Knockouth0
(0)

Sec8 CRISPR/Cas9 KO Plasmid (m)

sc-422866Gene Knockoutm0
(0)

Sec61α1 CRISPR/Cas9 KO Plasmid (m)

sc-424716Gene Knockoutm0
(0)

Sec61α2 CRISPR/Cas9 KO Plasmid (m)

sc-425419Gene Knockoutm0
(0)

Sec61β CRISPR/Cas9 KO Plasmid (m)

sc-425892Gene Knockoutm0
(0)

Sec31A CRISPR/Cas9 KO Plasmid (m)

sc-427321Gene Knockoutm0
(0)

Sec63 CRISPR/Cas9 KO Plasmid (m)

sc-431236Gene Knockoutm0
(0)

Sec24C CRISPR/Cas9 KO Plasmid (m)

sc-432324Gene Knockoutm0
(0)

Sec61α2 HDR Plasmid (h)

sc-402223-HDRHomology Directed Repairh0
(0)

Sec6 HDR Plasmid (h)

sc-405053-HDRHomology Directed Repairh0
(0)

Sec10 HDR Plasmid (h)

sc-406954-HDRHomology Directed Repairh0
(0)

Sec62 HDR Plasmid (h)

sc-407292-HDRHomology Directed Repairh0
(0)

Sec15B HDR Plasmid (h)

sc-407519-HDRHomology Directed Repairh0
(0)

Sec63 HDR Plasmid (h)

sc-407766-HDRHomology Directed Repairh0
(0)

Sec61α2 HDR Plasmid (m)

sc-425419-HDRHomology Directed Repairm0
(0)

Sec31A HDR Plasmid (m)

sc-427321-HDRHomology Directed Repairm0
(0)

Sec63 HDR Plasmid (m)

sc-431236-HDRHomology Directed Repairm0
(0)

Sec24C HDR Plasmid (m)

sc-432324-HDRHomology Directed Repairm0
(0)

Sec CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Sec5 Double Nickase Plasmid (h)

sc-405088-NICGene Knockouth0
(0)

Sec5 Double Nickase Plasmid (h2)

sc-405088-NIC-2Gene Knockouth0
(0)

Sec CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Sec61α1 CRISPR Activation Plasmid (h)

sc-402222-ACTGene Activationh0
(0)

Sec61α2 CRISPR Activation Plasmid (h)

sc-402223-ACTGene Activationh0
(0)

Sec61β CRISPR Activation Plasmid (h)

sc-402791-ACTGene Activationh0
(0)

Sec8 CRISPR Activation Plasmid (h)

sc-405009-ACTGene Activationh0
(0)

Sec6 CRISPR Activation Plasmid (h)

sc-405053-ACTGene Activationh0
(0)

Sec5 CRISPR Activation Plasmid (h)

sc-405088-ACTGene Activationh0
(0)

Sec61α1 CRISPR Activation Plasmid (h2)

sc-402222-ACT-2Gene Activationh0
(0)

Sec61α2 CRISPR Activation Plasmid (h2)

sc-402223-ACT-2Gene Activationh0
(0)

Sec61β CRISPR Activation Plasmid (h2)

sc-402791-ACT-2Gene Activationh0
(0)