Date published: 2026-5-24

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Sec CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. Sec gene silencers are available as Sec CRISPR/Cas9 Knockout plasmids and Sec Double Nickase Plasmids. Sec CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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Sec CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sec5 Double Nickase Plasmid (h)

sc-405088-NIChGene KnockoutPuromycin0
(0)

Sec5 Double Nickase Plasmid (h2)

sc-405088-NIC-2hGene KnockoutPuromycin0
(0)

Sec6 CRISPR/Cas9 KO Plasmid (h)

sc-405053hGene KnockoutGFP0
(0)

Sec6 HDR Plasmid (h)

sc-405053-HDRhHomology Directed RepairPuromycin0
(0)

Sec8 CRISPR/Cas9 KO Plasmid (m)

sc-422866mGene KnockoutGFP0
(0)

Sec10 HDR Plasmid (h)

sc-406954-HDRhHomology Directed RepairPuromycin0
(0)

Sec15A CRISPR/Cas9 KO Plasmid (h)

sc-405860hGene KnockoutGFP0
(0)

Sec15B CRISPR/Cas9 KO Plasmid (h)

sc-407519hGene KnockoutGFP0
(0)

Sec15B HDR Plasmid (h)

sc-407519-HDRhHomology Directed RepairPuromycin0
(0)

Sec24C CRISPR/Cas9 KO Plasmid (m)

sc-432324mGene KnockoutGFP0
(0)

Sec24C HDR Plasmid (m)

sc-432324-HDRmHomology Directed RepairPuromycin0
(0)

Sec31A CRISPR/Cas9 KO Plasmid (m)

sc-427321mGene KnockoutGFP0
(0)

Sec31A HDR Plasmid (m)

sc-427321-HDRmHomology Directed RepairPuromycin0
(0)

Sec61β CRISPR/Cas9 KO Plasmid (m)

sc-425892mGene KnockoutGFP0
(0)

Sec62 CRISPR/Cas9 KO Plasmid (h)

sc-407292hGene KnockoutGFP0
(0)

Sec62 HDR Plasmid (h)

sc-407292-HDRhHomology Directed RepairPuromycin0
(0)

Sec63 CRISPR/Cas9 KO Plasmid (h)

sc-407766hGene KnockoutGFP0
(0)

Sec63 HDR Plasmid (h)

sc-407766-HDRhHomology Directed RepairPuromycin0
(0)

Sec63 CRISPR/Cas9 KO Plasmid (m)

sc-431236mGene KnockoutGFP0
(0)

Sec63 HDR Plasmid (m)

sc-431236-HDRmHomology Directed RepairPuromycin0
(0)

Sec61α1 CRISPR/Cas9 KO Plasmid (m)

sc-424716mGene KnockoutGFP0
(0)

Sec61α2 CRISPR/Cas9 KO Plasmid (h)

sc-402223hGene KnockoutGFP0
(0)

Sec61α2 HDR Plasmid (h)

sc-402223-HDRhHomology Directed RepairPuromycin0
(0)

Sec61α2 CRISPR/Cas9 KO Plasmid (m)

sc-425419mGene KnockoutGFP0
(0)

Sec61α2 HDR Plasmid (m)

sc-425419-HDRmHomology Directed RepairPuromycin0
(0)

Sec CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sec5 CRISPR Activation Plasmid (h)

sc-405088-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sec6 CRISPR Activation Plasmid (h)

sc-405053-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sec8 CRISPR Activation Plasmid (h)

sc-405009-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sec61β CRISPR Activation Plasmid (h)

sc-402791-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sec61β CRISPR Activation Plasmid (h2)

sc-402791-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 CRISPR Activation Plasmid (h)

sc-402222-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sec61α1 CRISPR Activation Plasmid (h2)

sc-402222-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 CRISPR Activation Plasmid (h)

sc-402223-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sec61α2 CRISPR Activation Plasmid (h2)

sc-402223-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)