SCML2 Inhibitors
SCML2 Inhibitors belong to a distinct chemical class that has garnered significant attention in the field of molecular biology and cellular research. These compounds are specifically designed to target and modulate the activity of the SCML2 protein, which is an integral component of the Polycomb repressive complex 1 (PRC1). SCML2, short for Sex Comb on Midleg-Like 2, is a protein that plays a crucial role in gene regulation and epigenetic control. It is involved in maintaining gene silencing, primarily by facilitating the binding of PRC1 to chromatin, leading to the repression of gene transcription.
Structurally, SCML2 Inhibitors are meticulously crafted molecules that possess the capability to bind to SCML2 with high affinity. This binding interaction disrupts the normal function of SCML2 within the PRC1 complex, ultimately impacting the epigenetic landscape of cells. By inhibiting SCML2, these compounds can potentially alter the pattern of gene expression, unlocking new avenues for research into gene regulation and cellular processes. Researchers have been keenly exploring the precise mechanisms by which SCML2 Inhibitors exert their effects, aiming to elucidate the intricate details of how SCML2 functions in epigenetic control.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that can alter chromatin structure and potentially affect SCML2-mediated gene silencing. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Targets EZH2, a component of the PRC2 complex, which can indirectly affect SCML2 function by altering histone methylation patterns. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $92.00 $243.00 $306.00 | ||
Selective EZH2 inhibitor that can disrupt Polycomb Repressive Complex 2 (PRC2) function, potentially influencing SCML2 activity. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
An EZH2 inhibitor that can modify histone methylation, potentially impacting SCML2's role in transcriptional repression. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
DNA methyltransferase inhibitor that may impact SCML2 indirectly by changing DNA methylation patterns and chromatin structure. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $126.00 | 5 | |
Inhibits histone methyltransferases, which could affect the chromatin context within which SCML2 operates. | ||||||
PFI-1 | 1403764-72-6 | sc-478504 | 5 mg | $98.00 | ||
BET bromodomain inhibitor that, while not directly targeting SCML2, can affect gene expression regulation in which SCML2 might play a part. | ||||||