SATB1 Inhibitors
SATB1 inhibitors belong to a specific chemical class of compounds designed to target and modulate the activity of the Special AT-rich sequence-binding protein 1 (SATB1). SATB1 is a DNA-binding protein that plays a crucial role in gene regulation and chromatin organization. By binding to AT-rich DNA sequences, SATB1 can influence the folding of chromatin, leading to changes in gene expression patterns. SATB1 inhibitors are designed to selectively hinder the interactions between SATB1 and its target DNA, thereby interrupting its regulatory effects on gene expression.
These inhibitors act by competitively occupying the DNA-binding domain of SATB1, preventing its normal function and leading to altered chromatin conformation. As a result, the transcriptional regulation of various genes is affected, potentially offering researchers a valuable tool to study the specific roles of SATB1 in cellular processes. The development and use of SATB1 inhibitors have provided valuable insights into the molecular mechanisms of gene regulation and chromatin dynamics, contributing to the advancement of basic scientific knowledge in the field of molecular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5′-Deoxy-5′-methylthioadenosine | 2457-80-9 | sc-202427 | 50 mg | $122.00 | 1 | |
A small molecule inhibitor that binds to the DNA-binding domain of SATB1, preventing its interaction with target gene promoters. | ||||||
SJ 172550 | 431979-47-4 | sc-357403 sc-357403A | 10 mg 50 mg | $175.00 $737.00 | 1 | |
A selective SATB1 inhibitor that disrupts the interaction between SATB1 and its target DNA sequences, inhibiting gene expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
This is a derivative of vitamin A and has been shown to downregulate SATB1 expression, leading to altered gene expression patterns. | ||||||
Salinomycin | 53003-10-4 | sc-253530 sc-253530C sc-253530A sc-253530B | 5 mg 10 mg 25 mg 100 mg | $162.00 $241.00 $406.00 $474.00 | 1 | |
Originally identified as an antibiotic, it has been found to inhibit SATB1 expression and has potential anti-cancer properties. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A natural flavonoid found in various plants, which has been reported to inhibit SATB1 activity and suppress cancer cell growth. | ||||||
TEMPOL | 2226-96-2 | sc-200825 | 1 g | $38.00 | 33 | |
An antioxidant and free radical scavenger that has been shown to downregulate SATB1 expression and may influence cancer progression. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
A polyphenol found in fruits and nuts, which has demonstrated SATB1 inhibitory effects in certain studies. | ||||||
Cucurbitacin B | 6199-67-3 | sc-483515 | 5 mg | $183.00 | ||
A triterpenoid compound found in various plants that has shown inhibition of SATB1 expression and metastasis in certain cancers. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A demethylating agent that can alter SATB1 expression patterns by influencing DNA methylation. | ||||||