SAP 30BP Inhibitors
SAP 30BP Inhibitors predominantly revolves around compounds that influence histone deacetylase (HDAC) activities and other epigenetic markers. Trichostatin A, SAHA, Romidepsin, Valproic Acid, Mocetinostat, and Entinostat are HDAC inhibitors. These chemicals play a crucial role in the modulation of acetylation states of histones, which in turn affect the structure and accessibility of chromatin. As SAP30BP is associated with the Sin3-HDAC complex, these inhibitors can modulate the activity of this complex and, by extension, SAP30BP.
Another significant subset of this class are the BET bromodomain inhibitors, namely JQ1 and I-BET151. These compounds hinder the binding of BET proteins to acetylated histones, potentially affecting the transcriptional regulation and chromatin structure that SAP30BP may influence. Lastly, the chemical class includes inhibitors targeting histone methyltransferases (HMTs) like Chaetocin, UNC0638, BIX-01294, and EPZ005687. These inhibitors modulate the methylation states of histones, further affecting chromatin dynamics and potentially the pathways or processes where SAP30BP is involved.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
HDAC inhibitor, can affect the activity of Sin3-HDAC complexes associated with SAP30BP. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
HDAC inhibitor that can modulate the activity of complexes related to SAP30BP. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
HDAC inhibitor, potentially affects protein deacetylation associated with SAP30BP. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Weak HDAC inhibitor, can influence the chromatin remodeling processes associated with SAP30BP. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $214.00 $247.00 $1463.00 | 2 | |
HDAC inhibitor, potentially influences the epigenetic regulation where SAP30BP might be involved. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
HDAC inhibitor that can modulate protein interactions related to SAP30BP. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
BET bromodomain inhibitor, affects transcriptional regulation which can impact SAP30BP associated pathways. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
BET bromodomain inhibitor, affects chromatin structure potentially impacting SAP30BP function. | ||||||
UNC0638 | 1255580-76-7 | sc-397012 | 10 mg | $315.00 | ||
G9a and GLP HMT inhibitor, can influence chromatin states potentially affecting SAP30BP. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $37.00 $112.00 $408.00 | ||
HMT inhibitor specifically against G9a, can modulate chromatin-related functions of SAP30BP. | ||||||