RyR-2 Activators
RyR-2 activators belong to a distinctive category of chemical compounds designed to interact with and modulate the activity of the Ryanodine receptor type 2 (RyR-2), a calcium-release channel primarily found in cardiac muscle cells. RyR-2 plays a pivotal role in regulating calcium homeostasis within cardiomyocytes, controlling the release of calcium ions from the sarcoplasmic reticulum into the cytoplasm, which is a critical step in the excitation-contraction coupling of the heart muscle. These activators are engineered to directly or indirectly affect the functioning of RyR-2, enabling researchers to investigate the intricate molecular mechanisms and signaling pathways governed by this receptor.
The mechanisms through which RyR-2 activators operate can vary widely, but their common aim is to facilitate scientific exploration of RyR-2's roles within the context of cardiac physiology. By modulating RyR-2 activity, researchers can delve into its contributions to cardiac contractility, rhythm, and overall heart function. This research provides valuable insights into the complex interplay between calcium handling, ion channels, and excitation-contraction coupling in cardiac muscle. The study of RyR-2 activators contributes to our broader understanding of the intricate molecular processes that underlie cardiac function, which is essential for maintaining cardiovascular health.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol may modulate RyR-2 expression by influencing signaling pathways related to calcium homeostasis and oxidative stress in cardiac cells. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin potentially affects RyR-2 expression through its anti-inflammatory and antioxidant properties, which can influence cardiac muscle cell function. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine is known to interact with RyR-2, potentially altering its expression by modulating calcium signaling pathways in cardiac cells. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin may influence RyR-2 expression by affecting cellular oxidative stress responses and calcium signaling in cardiac muscle. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This compound from green tea might affect RyR-2 expression by modulating signaling pathways related to oxidative stress and calcium homeostasis in heart cells. | ||||||
Taurine | 107-35-7 | sc-202354 sc-202354A | 25 g 500 g | $47.00 $100.00 | 1 | |
Taurine might influence RyR-2 expression by modulating osmoregulation and calcium signaling pathways in cardiac muscle cells. | ||||||
12β-Hydroxydigitoxin | 20830-75-5 | sc-213604 sc-213604A | 1 g 5 g | $140.00 $680.00 | ||
12β-Hydroxydigitoxin might influence RyR-2 expression by impacting calcium handling and signaling in cardiac muscle cells. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Isoproterenol may modulate RyR-2 expression by activating beta-adrenergic receptors, which impacts calcium signaling in cardiac cells. | ||||||