RyR-1 Antibodies

Santa Cruz Biotechnology offers a broad range of RyR-1 monoclonal antibodies for research in muscle physiology and related fields. RyR-1 monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). RyR-1, or Ryanodine Receptor 1, plays a critical role in calcium release from the sarcoplasmic reticulum in skeletal muscle cells, which is essential for muscle contraction. Dysregulation of RyR-1 has been implicated in several muscle disorders, including malignant hyperthermia and central core disease, making it a significant target for research. Understanding the function and regulation of RyR-1 is crucial for developing therapeutic strategies for muscle-related conditions. Researchers can investigate calcium signaling pathways and their impact on muscle function using RyR-1 monoclonal antibodies. Advanced detection methods, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC) conjugates, enable precise visualization of RyR-1 localization and interactions. The specificity and reliability of Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of muscle physiology and developing potential treatments for muscle disorders.