RyR-1 Antibody (8.U.100): sc-71989
- RyR-1 Antibody (8.U.100) is a mouse monoclonal mouse IgM κ κ provided at 200 µg/ml
- raised against skeletal muscle triads of rabbit origin
- recommended for detection of skeletal muscle ryanodine receptor Ca2+ channel of mouse, rat, rabbit and canine origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for RyR-1 Antibody (8.U.100). This work is in progress.
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RyR-1 Antibody (8.U.100) is a mouse monoclonal IgM antibody that detects RyR-1 in mouse, rat, rabbit, and canine samples through western blotting (WB) and immunoprecipitation (IP) applications. RyR-1, a member of the ryanodine receptor family, plays a crucial role in calcium signaling within muscle cells, specifically in the excitation-contraction coupling process. Located primarily in the sarcoplasmic reticulum of skeletal muscle, RyR-1 is responsible for the release of calcium ions in response to membrane depolarization, which is essential for muscle contraction. The proper functioning of RyR-1 is vital, as any mutations in its gene can lead to severe muscle disorders such as Brody disease, malignant hyperthermia, cardiomyopathy, and central core disease. Anti-RyR-1 antibody (8.U.100) enables researchers to effectively study the expression and regulation of RyR-1, contributing to a better understanding of muscle physiology and the pathophysiology of related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RyR-1 Antibody (8.U.100) | sc-71989 | 200 µg/ml | $322.00 |