The class of chemicals identified as Rslcan-7 Activators includes compounds that can influence the activity of the Rslcan-7 protein through various biological mechanisms. These activators are capable of modulating cellular pathways to indirectly promote the function of Rslcan-7, typically without directly binding to the protein itself. Such activation processes involve interactions with cellular signaling cascades that eventually lead to the upregulation or enhanced function of Rslcan-7. The activators operate by manipulating different molecular targets, each playing a distinct role in the intricate network of intracellular processes. For instance, some of these compounds can initiate their effect by interacting with enzymes that regulate the levels of secondary messengers within the cell, such as cyclic AMP. The increased concentration of these messengers can then stimulate protein kinases that phosphorylate transcription factors, which in turn can elevate the expression levels or functional activity of Rslcan-7.
Additionally, other compounds in the Rslcan-7 Activators class work by altering the epigenetic landscape of the cell. By inhibiting enzymes responsible for DNA methylation or by preventing the deacetylation of histones, these activators can lead to a more open chromatin structure around the genes that control the expression of Rslcan-7. This change in the chromatin state can facilitate the transcription of Rslcan-7, effectively increasing its activity. Moreover, some activators target various kinases that are part of signaling pathways, affecting the phosphorylation states of proteins that are upstream regulators of Rslcan-7. Through these diverse but interconnected mechanisms, chemicals classified as Rslcan-7 Activators are capable of modulating the activity of this protein, thus influencing the cellular functions it controls. Each activator employs a unique mechanism to contribute to the regulation of Rslcan-7, reflecting the complexity of cellular homeostasis and gene expression regulation.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, leading to increased levels of cAMP, which can activate PKA. PKA can phosphorylate transcription factors, enhancing their activity, which could possibly activate Zfp458. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Inhibits DNA methyltransferases, resulting in DNA hypomethylation, potentially leading to the activation of genes that could possibly activate Zfp458. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Modulates various signaling pathways and gene expression, which may include genes that could possibly activate Zfp458. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Binds retinoic acid receptors, affecting gene expression, which can include genes that could possibly activate Zfp458. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Acts as a tyrosine kinase inhibitor, potentially affecting cell signaling and transcription factor activity that could possibly activate Zfp458. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor that may impact the MAPK/ERK pathway, possibly influencing transcription factors that could possibly activate Zfp458 expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, potentially altering the activity of transcription factors that could possibly activate Zfp458. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, which may influence transcription factor activity and expression of Zfp458, potentially activating it. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor affecting AKT signaling, which can influence transcription factor activity, possibly impacting Zfp458 expression, potentially activating it. | ||||||
LGK 974 | 1243244-14-5 | sc-489380 sc-489380A | 5 mg 50 mg | $352.00 $1270.00 | 2 | |
Inhibits Wnt production, potentially affecting pathways that regulate transcription factors associated with Zfp458 expression, possibly activating it. | ||||||