RhBG Inhibitors
RhBG inhibitors are primarily characterized by their ability to modulate the ammonia transport and metabolism process. Ammonia plays a crucial role in various physiological processes, and its tight regulation is essential for maintaining cellular homeostasis. Acetazolamide and Methazolamide are carbonic anhydrase inhibitors that impact bicarbonate reabsorption in kidneys. Bicarbonate is closely linked to ammonia transport, and its modulation can indirectly affect the function of RhBG. Another pertinent compound is L-NAME, an inhibitor of nitric oxide synthase. Nitric oxide is intertwined with ammonia metabolism, and any changes in its levels can influence RhBG's operational environment.
Furthermore, compounds such as 6-Diazo-5-oxo-L-norleucine (DON) and Azaserine specifically inhibit glutamine synthetase, a pivotal enzyme in ammonia metabolism. Their action can indirectly modulate the functional context of RhBG. High phosphate concentrations are also known to influence ammonia transport mechanisms, making phosphate a potential indirect modulator of RhBG function. Additionally, compounds like Tannic acid, which have broader cellular impacts, can modulate ammonia metabolism and subsequently RhBG's role.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetazolamide | 59-66-5 | sc-214461 sc-214461A sc-214461B sc-214461C sc-214461D sc-214461E sc-214461F | 10 g 25 g 100 g 250 g 500 g 1 kg 2 kg | $81.00 $177.00 $434.00 $541.00 $883.00 $1479.00 $2244.00 | 1 | |
Carbonic anhydrase inhibitor that impedes bicarbonate reabsorption in kidneys, indirectly affecting ammonia transport. | ||||||
Methazolamide | 554-57-4 | sc-235615 | 1 g | $94.00 | 3 | |
Another carbonic anhydrase inhibitor, impacting bicarbonate and proton secretion, indirectly influencing RhBG activity. | ||||||
L-NG-Nitroarginine Methyl Ester (L-NAME) | 51298-62-5 | sc-200333 sc-200333A sc-200333B | 1 g 5 g 25 g | $48.00 $107.00 $328.00 | 45 | |
Inhibitor of nitric oxide synthase, affecting nitric oxide production, which plays a role in ammonia metabolism. | ||||||
6-Diazo-5-oxo-L-norleucine | 157-03-9 | sc-227078 sc-227078A sc-227078B sc-227078C | 5 mg 25 mg 100 mg 250 mg | $88.00 $291.00 $926.00 $2195.00 | ||
Glutamine synthetase inhibitor that modulates ammonia metabolism in cells, indirectly affecting RhBG's functional context. | ||||||
Sodium Phosphate, Dibasic | 7558-79-4 | sc-203277 sc-203277A sc-203277D sc-203277B sc-203277C | 500 g 1 kg 2 kg 5 kg 10 kg | $57.00 $176.00 $239.00 $380.00 $588.00 | 11 | |
High phosphate concentration can indirectly affect ammonia transport processes, potentially impacting RhBG function. | ||||||
Gallotannin | 1401-55-4 | sc-202619 sc-202619A sc-202619B sc-202619C sc-202619D sc-202619E sc-202619F | 1 g 10 g 100 g 250 g 1 kg 2.5 kg 5 kg | $26.00 $37.00 $67.00 $78.00 $234.00 $536.00 $983.00 | 12 | |
Known to interfere with various cellular processes, potentially modulating ammonia metabolism and RhBG's role in it. | ||||||
Hydroxylamine solution | 7803-49-8 | sc-250136 | 100 ml | $72.00 | ||
Can influence cellular ammonia levels, thereby potentially modulating the functional environment of RhBG. | ||||||
Azaserine | 115-02-6 | sc-29063 sc-29063A | 50 mg 250 mg | $312.00 $924.00 | 15 | |
Glutamine synthetase inhibitor that can modulate ammonia metabolism, indirectly impacting RhBG's operational context. | ||||||
L-Mimosine | 500-44-7 | sc-201536A sc-201536B sc-201536 sc-201536C | 25 mg 100 mg 500 mg 1 g | $36.00 $88.00 $220.00 $436.00 | 8 | |
Affects various cellular metabolic pathways, including those involved in ammonia metabolism, potentially influencing RhBG. | ||||||
6-Mercaptopurine | 50-44-2 | sc-361087 sc-361087A | 50 mg 100 mg | $72.00 $104.00 | ||
Impacts purine metabolism, which has downstream effects on ammonia levels and potentially on RhBG function. | ||||||