The chemical class identified as RGPD6 Inhibitors refers to a category of compounds designed to selectively target the molecular entity RGPD6. The RGPD6 gene encodes a member of the RANBP2 family, a group known for its involvement in nucleocytoplasmic transport and gene expression regulation. While the essential roles of RGPD6 within cellular processes are acknowledged, the specific functions and interactions remain a subject of ongoing research. Inhibitors belonging to the RGPD6 Inhibitors class are meticulously designed molecules with the primary objective of modulating the activity or function of RGPD6, thereby inducing an inhibitory effect. Researchers in this field utilize a multidisciplinary approach, incorporating insights from structural biology, medicinal chemistry, and computational modeling to unravel the complex molecular interactions between the inhibitors and the target RGPD6.
Structurally, RGPD6 Inhibitors are characterized by their specific molecular features carefully designed to facilitate selective binding to RGPD6. This selectivity is paramount to minimize unintended effects on other cellular components, ensuring a focused impact on the intended molecular target. The development of inhibitors within this chemical class involves a comprehensive exploration of structure-activity relationships, optimization of pharmacokinetic properties, and a deep understanding of the molecular mechanisms associated with RGPD6. As researchers delve deeper into the functional aspects of RGPD6 Inhibitors, the knowledge generated contributes not only to deciphering the specific roles of RGPD6 but also to advancing our broader comprehension of cellular processes and molecular regulation. The exploration of RGPD6 Inhibitors represents a significant avenue for expanding fundamental knowledge in molecular pharmacology and cellular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
This antibiotic binds to DNA and inhibits RNA polymerase, potentially decreasing the transcription of various genes including RGPD6. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide can inhibit RNA polymerase II, which could lead to reduced transcription of multiple genes such as RGPD6. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin specifically inhibits RNA polymerase II, leading to decreased mRNA synthesis that may include mRNA for RGPD6. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin interferes with mRNA elongation and polyadenylation, potentially leading to decreased RGPD6 mRNA levels. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II transcriptional elongation, which could result in lower expression of genes including RGPD6. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide blocks protein synthesis by inhibiting ribosomal translocation, which may affect RGPD6 protein levels. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin causes premature chain termination during protein synthesis, possibly reducing the synthesis of proteins such as RGPD6. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol inhibits cyclin-dependent kinases, potentially affecting transcription and thereby potentially reducing RGPD6 expression. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 disrupts BET bromodomain interactions, potentially altering chromatin structure and gene transcription including RGPD6. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, an HDAC inhibitor, can change chromatin structure and downregulate gene expression, which may affect RGPD6 transcription. | ||||||