Reg Iβ Activators
Reg Iβ, also known as Regenerating Family Member 1 Beta (REG1B), is a protein that is encoded by the REG1B gene in humans. Similar to Reg Iα, it's part of the regenerating gene (REG) family, which was initially identified during studies on pancreatic islet regeneration.Reg Iβ is primarily expressed in the gastrointestinal tract, with the highest levels seen in the stomach and the small intestine. It plays a role in the maintenance and repair of the gastrointestinal tract by promoting cellular proliferation and differentiation and has anti-apoptotic effects that help protect cells from programmed cell death.
Studies have also shown that Reg Iβ is overexpressed in several types of gastrointestinal cancers, including gastric and colorectal cancers, suggesting it might play a role in tumor growth and progression. This overexpression has been associated with cancer aggressiveness and poor prognosis, which indicates that Reg Iβ might serve as a biomarker for these cancers.In addition to its role in cancer, Reg Iβ has been associated with inflammation and immune responses.
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Items 11 to 19 of 19 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin disrupts calcium storage and activates stress-response kinases, which could phosphorylate and activate Reg I β. | ||||||
Vitamin A | 68-26-8 | sc-280187 sc-280187A | 1 g 10 g | $385.00 $2654.00 | ||
A form of Vitamin A; involved in growth and differentiation, potentially affecting Reg Iβ. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Known for its anti-inflammatory properties and influence on cell proliferation, could affect Reg Iβ. | ||||||
Spermine | 71-44-3 | sc-212953A sc-212953 sc-212953B sc-212953C | 1 g 5 g 25 g 100 g | $61.00 $196.00 $277.00 $901.00 | 1 | |
A polyamine involved in cell growth and regeneration, could have indirect effects on Reg Iβ. | ||||||
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $41.00 $77.00 $153.00 | ||
A thyroid hormone that influences various metabolic processes, potentially impacting Reg Iβ. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Hydrogen peroxide can induce oxidative stress response pathways, activating various kinases that can phosphorylate and activate Reg I β. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A disrupts the Golgi structure, activating stress kinases that could phosphorylate and activate Reg I β. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid inhibits protein phosphatases PP1 and PP2A, leading to increased phosphorylation and activation of Reg I β. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK, involved in the MAPK/ERK pathway, could indirectly modulate Reg Iβ activity. | ||||||