The class of RBM26 Activators refers to chemicals that can indirectly influence the function of the RBM26 protein. These chemicals do not directly bind to or interact with RBM26 but instead modulate the pathways or cellular processes that RBM26 is involved in. This includes a variety of cellular signaling pathways and epigenetic processes.
The chemicals that fall under this class have diverse mechanisms of action but are grouped together because of their potential to modulate RBM26 function. They include mTOR inhibitors, SIRT1 activators, AMPK activators, PI3K inhibitors, DNA methyltransferase inhibitors, GSK3B inhibitors, ERK inhibitors, TGF-beta inhibitors, ROCK inhibitors, JNK inhibitors, MEK1/2 inhibitors, and G9a/GLP methyltransferase inhibitors. These chemicals can influence pathways such as mTOR signaling, SIRT1-mediated stress response, AMPK-mediated energy regulation, PI3K/Akt signaling, DNA methylation, GSK3B-related pathways, ERK signaling, TGF-beta signaling, ROCK-related pathways, JNK signaling, MAPK signaling, and histone methylation. By modulating these pathways and epigenetic processes, these chemicals can in turn influence the RNA splicing and other RNA processes that RBM26 is involved in.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that regulates protein synthesis and cell growth. By inhibiting mTOR, Rapamycin can affect the cellular processes that RBM26 is involved in, such as RNA splicing. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A compound known to activate SIRT1, a protein involved in stress response and aging. SIRT1 activation can influence the epigenetic modifications of RNA, which RBM26 is involved in. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
An AMPK activator that influences cellular energy status. AMPK activation can lead to changes in transcription and translation processes, potentially modulating RBM26 function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor which can affect downstream signaling pathways, such as the Akt/mTOR pathway. This could influence RBM26, as it plays a role in RNA splicing and other RNA processes. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, which can affect the epigenetic status of genes. This change in epigenetic status can indirectly affect RBM26 function, which plays a role in RNA processes. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $57.00 $184.00 $867.00 | 10 | |
An inhibitor of GSK3B, a protein involved in many signaling pathways. By inhibiting GSK3B, this could indirectly affect RBM26's role in RNA processes. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An ERK inhibitor that can affect downstream signaling pathways, potentially influencing RBM26's role in RNA splicing and other RNA processes. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
An inhibitor of the TGF-beta signaling pathway, which can influence cellular processes such as cell growth and differentiation. This may indirectly modulate the function of RBM26. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
An inhibitor of ROCK, a protein that plays a role in many cellular processes. By inhibiting ROCK, this may indirectly modulate the function of RBM26. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $65.00 $267.00 | 257 | |
A JNK inhibitor that can affect downstream signaling pathways, potentially influencing RBM26's role in RNA splicing and other RNA processes. |