R-Spondin2 Inhibitors
The chemical class of R-Spondin2 Inhibitors includes various compounds that can potentially suppress or modulate the expression and activity of R-Spondin2, mainly through their effects on Wnt signaling and related cellular pathways. This class encompasses Wnt signaling antagonists such as DKK1 mimetics, SFRP mimetics, ICG-001, XAV939, JW55, and PKF118-310, which specifically target different aspects of the Wnt pathway, potentially leading to reduced R-Spondin2 activity.
Porcupine inhibitors like LGK-974, which prevent Wnt ligand secretion, and antihelminthic drugs like Niclosamide that inhibit Wnt/β-catenin signaling, are included due to their potential impact on R-Spondin2. Immunosuppressants like Cyclosporine A and mTOR inhibitors such as Rapamycin can affect various signaling pathways and processes, potentially influencing R-Spondin2. Corticosteroids, known for modulating immune responses, and compounds like Salinomycin, with their effects on Wnt signaling, are also considered for their potential to impact R-Spondin2 expression and activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Canertinib | 267243-28-7 | sc-207397 | 10 mg | $260.00 | 3 | |
A specific inhibitor of the Wnt/β-catenin signaling pathway that might indirectly inhibit R-Spondin2. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $36.00 $117.00 $525.00 | 26 | |
A small molecule that inhibits Wnt signaling by promoting β-catenin degradation, potentially reducing R-Spondin2 activity. | ||||||
JW 55 | 664993-53-7 | sc-364517 sc-364517A | 10 mg 50 mg | $172.00 $726.00 | ||
An inhibitor of the Wnt/β-catenin pathway, which could indirectly decrease R-Spondin2 activity. | ||||||
PKF118-310 | 84-82-2 | sc-364590 sc-364590A | 5 mg 25 mg | $180.00 $651.00 | ||
A Wnt signaling antagonist that could lead to reduced R-Spondin2 activity. | ||||||
LGK 974 | 1243244-14-5 | sc-489380 sc-489380A | 5 mg 50 mg | $359.00 $1295.00 | 2 | |
A porcupine inhibitor that prevents Wnt ligand secretion and thus might indirectly inhibit R-Spondin2. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
An immunosuppressant that could potentially modulate signaling pathways involving R-Spondin2. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can affect various cellular processes, potentially including pathways related to R-Spondin2. | ||||||
Prednisone | 53-03-2 | sc-205816 sc-205816A sc-205816B | 1 g 5 g 25 g | $42.00 $136.00 $676.00 | 2 | |
Can modulate immune and inflammatory responses, potentially influencing pathways associated with R-Spondin2. | ||||||
Salinomycin | 53003-10-4 | sc-253530 sc-253530C sc-253530A sc-253530B | 5 mg 10 mg 25 mg 100 mg | $162.00 $241.00 $406.00 $474.00 | 1 | |
Known to inhibit Wnt/β-catenin signaling, salinomycin might indirectly affect R-Spondin2 activity. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $38.00 $79.00 $188.00 $520.00 $1248.00 $5930.00 | 8 | |
An antihelminthic drug that has been shown to inhibit the Wnt/β-catenin signaling pathway, potentially leading to the downregulation of R-Spondin2. | ||||||