PTD015 Activators
These mechanisms range from epigenetic modifications (like DNA demethylation by 5-Azacytidine and histone deacetylation inhibition by Trichostatin A) to modulation of signal transduction pathways (such as cAMP pathway activation by Forskolin and PKC activation by PMA).
Compounds like Retinoic Acid and Dexamethasone exert their effects through receptor-mediated pathways, influencing the transcription of various genes in processes like cell differentiation and inflammation. Rapamycin and TGF-beta affect key cellular signaling pathways like mTOR and TGF-beta signaling, respectively, which are crucial in cell growth and differentiation. Lithium Chloride, through its inhibition of GSK-3, and EGCG, with its broad-spectrum effects on signaling pathways, represent compounds that modulate multiple cellular processes, including gene expression. Sodium Butyrate and Tamoxifen exert their effects through epigenetic and receptor-mediated mechanisms, respectively.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferase, leading to demethylation and potentially activating gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Histone deacetylase inhibitor, altering chromatin structure and potentially enhancing gene expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels and potentially influencing gene expression through cAMP response elements. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC), which can lead to activation of transcription factors and gene expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Binds to retinoic acid receptors, influencing gene expression related to cell differentiation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoid receptor agonist, can activate or repress a wide range of genes. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
Cytokine that activates TGF-beta signaling pathway, influencing cell proliferation and differentiation-related gene expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits GSK-3, leading to changes in Wnt signaling and potentially influencing gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Green tea polyphenol, affects various signaling pathways and could influence gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor, can lead to chromatin remodeling and activation of gene expression. | ||||||