PSK2 Activators is a term used to describe a specific class of chemical compounds that play a crucial role in modulating cellular processes within the human body. These activators are primarily associated with their ability to interact with the PSK2 protein, a significant player in various cellular functions. PSK2, short for "Protein Serine/Threonine Kinase 2," is an enzyme responsible for catalyzing the transfer of phosphate groups to specific serine and threonine residues of target proteins. This post-translational modification, known as phosphorylation, serves as a pivotal mechanism in regulating cellular signaling pathways.
Members of the PSK2 Activators class are characterized by their unique chemical structures, which allow them to bind to PSK2 with high affinity. This binding interaction leads to the activation of PSK2, triggering a cascade of downstream events within the cell. These downstream effects are wide-ranging and can include alterations in gene expression, changes in protein activity, and modifications to cellular processes such as cell growth, differentiation, and apoptosis. The activation of PSK2 by these compounds is crucial for maintaining cellular homeostasis and responding to various extracellular signals, making them important players in cellular biology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a classic PKC2 activator that mimics the action of diacylglycerol (DAG) and activates PKC2. | ||||||
Bryostatin 1 | 83314-01-6 | sc-201407 | 10 µg | $245.00 | 9 | |
Bryostatin-1 activates PKC2 by binding to its regulatory domain, similar to DAG, leading to PKC2 activation. | ||||||
Ingenol | 30220-46-3 | sc-202184 sc-202184A sc-202184B sc-202184C | 1 mg 5 mg 10 mg 25 mg | $69.00 $305.00 $446.00 $1120.00 | 1 | |
Ingenol activates PKC2 by interacting with its regulatory domain, inducing a conformational change in the enzyme. | ||||||
Prostratin | 60857-08-1 | sc-203422 sc-203422A | 1 mg 5 mg | $141.00 $541.00 | 24 | |
Prostratin activates PKC2 through its interaction with the regulatory domain, triggering PKC2 activation. | ||||||
Sapintoxin D | 80998-07-8 | sc-203254 sc-203254A | 1 mg 5 mg | $62.00 $187.00 | 1 | |
Sapintoxin D activates PKC2 by binding to its regulatory domain, similar to other PKC activators. | ||||||
(−)-Indolactam V | 90365-57-4 | sc-202182 sc-202182A | 300 µg 1 mg | $175.00 $350.00 | 1 | |
Indolactam V activates PKC2 by interacting with the regulatory domain, resulting in PKC2 activation. | ||||||
4α-Phorbol 12,13-didecanoate | 27536-56-7 | sc-201210 sc-201210A | 1 mg 5 mg | $188.00 $676.00 | 3 | |
This synthetic compound activates PKC2 by mimicking PMA's action, binding to the regulatory domain of PKC2. | ||||||
Bryostatin 2 | 87745-28-6 | sc-202086 sc-202086A | 10 µg 25 µg | $270.00 $750.00 | 1 | |
Bryostatin-2 activates PKC2 by binding to its regulatory domain, triggering PKC2 activation. | ||||||
Protopanaxatriol | 34080-08-5 | sc-204866 sc-204866A | 5 mg 10 mg | $180.00 $193.00 | ||
Protopanaxatriol activates PKC2, likely through interaction with the regulatory domain, initiating PKC2 activation. | ||||||