PRR23B activators represent a niche category within the broader realm of molecular biology and chemistry, focusing on the activation of the PRR23B gene product. PRR23B, or Proline-Rich 23B, is part of a family of proline-rich proteins, which are known for their repetitive sequences containing the amino acid proline. These proteins often play roles in cellular processes such as signaling, cell adhesion, and the assembly of the extracellular matrix. The specific function of PRR23B in these contexts, however, is less understood, making the study of compounds that can activate its expression or function an area of interest for elucidating its role within the cell. Activators of PRR23B may interact directly with the protein or its regulatory elements, leading to an increase in its activity or expression levels. This modulation can provide insights into PRR23B's involvement in cellular processes and its interaction with other cellular components.
The study of PRR23B activators involves a multidisciplinary approach, encompassing aspects of organic chemistry, molecular biology, and bioinformatics. By identifying and characterizing compounds that can enhance the activity of PRR23B, researchers aim to uncover the underlying mechanisms through which PRR23B influences cellular functions. This involves detailed analyses of the interaction between PRR23B activators and their target, including the binding affinity, specificity, and the resultant conformational changes in the protein structure. Furthermore, understanding the impact of PRR23B activation on cellular pathways requires comprehensive biochemical and genetic studies, such as gene expression analysis and the examination of downstream effects on cellular processes. Through these studies, the role of PRR23B in the cell can be better understood, contributing to the broader knowledge of protein function and regulation in biological systems.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid is a metabolite of vitamin A that regulates gene expression through nuclear receptors, potentially influencing diverse genes including PRR23B. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels and potentially upregulating genes through the cAMP response element-binding protein (CREB). | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), which can lead to the activation of transcription factors affecting gene expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methylation inhibitor that can lead to the upregulation of genes by preventing gene silencing via methylation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA inhibits histone deacetylases (HDACs), altering chromatin structure and potentially increasing the expression of certain genes. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is another HDAC inhibitor that can lead to hyperacetylation of histones and activation of gene transcription. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, found in green tea, can modulate epigenetic changes and may impact gene expression profiles in cells. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences several signaling pathways, including the Wnt pathway, and may affect gene expression indirectly. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a glucocorticoid that can regulate gene expression by activating glucocorticoid receptors. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
β-Estradiol binds estrogen receptors and can regulate gene expression in a diverse set of target genes. | ||||||