The term PPIAL4F Activators refers to a specific category of chemical compounds designed to modulate the activity of the PPIAL4F gene or protein. PPIAL4F, also known as Peptidylprolyl Isomerase A Like 4F, is a gene that encodes a protein belonging to the peptidyl-prolyl isomerase (PPIase) family. These enzymes play essential roles in catalyzing the cis-trans isomerization of peptidyl-prolyl bonds in proteins, which is a critical step in protein folding and conformational changes. The exact biological function and regulatory mechanisms of PPIAL4F are subjects of ongoing research within the field of molecular biology and biochemistry. Activators within the PPIAL4F Activators class typically consist of small molecules or chemical agents strategically engineered to interact with the PPIAL4F gene or protein, with the intention of enhancing its expression or influencing its functional capabilities. These activators serve as valuable tools for researchers to manipulate PPIAL4F-related processes and explore its potential functions within the context of protein folding and conformational changes.
The mechanism of action for PPIAL4F Activators may involve various aspects of gene regulation. These compounds could influence the binding of transcription factors to the promoter region of the PPIAL4F gene, potentially increasing its transcriptional activity and leading to higher PPIAL4F gene expression levels. Alternatively, they might affect post-translational modifications or interactions of the PPIAL4F protein, such as phosphorylation or protein-protein interactions, which can modulate its stability, function, or subcellular localization within the cell. Researchers and scientists employ PPIAL4F Activators in molecular and cellular biology studies to investigate the role of PPIAL4F in protein folding, isomerization of peptidyl-prolyl bonds, and potential implications in cellular processes. By selectively modulating the gene's activity or protein function, researchers can gain insights into its functions, regulatory mechanisms, and potential involvement in maintaining proper protein conformation and function, contributing to a deeper understanding of the molecular processes involving PPIAL4F and its significance in cellular biology. Overall, PPIAL4F Activators provide valuable tools for exploring the functions and regulatory mechanisms of this peptidyl-prolyl isomerase in the context of protein folding and conformational changes within cells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Cyclosporin A binds to cyclophilins, potentially affecting their expression, including PPIAL4F, as part of a feedback mechanism in immune regulation or protein folding processes. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin induces ER stress by inhibiting N-linked glycosylation, potentially leading to an upregulation of PPIAL4F as part of the unfolded protein response (UPR) to maintain protein folding capacity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin causes ER stress by depleting ER calcium stores, potentially affecting PPIAL4F expression as cells attempt to cope with disrupted protein folding and calcium homeostasis. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a synthetic glucocorticoid, can influence gene expression related to stress and immune responses, potentially including PPIAL4F as part of cellular adaptation mechanisms. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid influences cell differentiation and growth, which might include the upregulation of PPIAL4F as part of its effects on cellular metabolism and protein synthesis. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Hydrogen peroxide induces oxidative stress, potentially leading to an upregulation of PPIAL4F as part of the cellular antioxidant defense mechanisms. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has anti-inflammatory and antioxidant effects, potentially modulating the expression of PPIAL4F as part of the cellular response to oxidative stress and inflammation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, an HDAC inhibitor, can lead to histone hyperacetylation, potentially affecting the expression of genes like PPIAL4F involved in protein folding and stress response. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases cAMP levels, potentially affecting PPIAL4F expression as part of cAMP-mediated cellular signaling pathways. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, affects cell growth and autophagy, which could indirectly influence PPIAL4F expression as part of the cellular response to altered growth conditions. | ||||||