Date published: 2026-2-14

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PPIAL4F Activators

The term PPIAL4F Activators refers to a specific category of chemical compounds designed to modulate the activity of the PPIAL4F gene or protein. PPIAL4F, also known as Peptidylprolyl Isomerase A Like 4F, is a gene that encodes a protein belonging to the peptidyl-prolyl isomerase (PPIase) family. These enzymes play essential roles in catalyzing the cis-trans isomerization of peptidyl-prolyl bonds in proteins, which is a critical step in protein folding and conformational changes. The exact biological function and regulatory mechanisms of PPIAL4F are subjects of ongoing research within the field of molecular biology and biochemistry. Activators within the PPIAL4F Activators class typically consist of small molecules or chemical agents strategically engineered to interact with the PPIAL4F gene or protein, with the intention of enhancing its expression or influencing its functional capabilities. These activators serve as valuable tools for researchers to manipulate PPIAL4F-related processes and explore its potential functions within the context of protein folding and conformational changes.

The mechanism of action for PPIAL4F Activators may involve various aspects of gene regulation. These compounds could influence the binding of transcription factors to the promoter region of the PPIAL4F gene, potentially increasing its transcriptional activity and leading to higher PPIAL4F gene expression levels. Alternatively, they might affect post-translational modifications or interactions of the PPIAL4F protein, such as phosphorylation or protein-protein interactions, which can modulate its stability, function, or subcellular localization within the cell. Researchers and scientists employ PPIAL4F Activators in molecular and cellular biology studies to investigate the role of PPIAL4F in protein folding, isomerization of peptidyl-prolyl bonds, and potential implications in cellular processes. By selectively modulating the gene's activity or protein function, researchers can gain insights into its functions, regulatory mechanisms, and potential involvement in maintaining proper protein conformation and function, contributing to a deeper understanding of the molecular processes involving PPIAL4F and its significance in cellular biology. Overall, PPIAL4F Activators provide valuable tools for exploring the functions and regulatory mechanisms of this peptidyl-prolyl isomerase in the context of protein folding and conformational changes within cells.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$63.00
$92.00
$250.00
$485.00
$1035.00
$2141.00
69
(5)

Cyclosporin A binds to cyclophilins, potentially affecting their expression, including PPIAL4F, as part of a feedback mechanism in immune regulation or protein folding processes.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$172.00
$305.00
66
(3)

Tunicamycin induces ER stress by inhibiting N-linked glycosylation, potentially leading to an upregulation of PPIAL4F as part of the unfolded protein response (UPR) to maintain protein folding capacity.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Thapsigargin causes ER stress by depleting ER calcium stores, potentially affecting PPIAL4F expression as cells attempt to cope with disrupted protein folding and calcium homeostasis.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone, a synthetic glucocorticoid, can influence gene expression related to stress and immune responses, potentially including PPIAL4F as part of cellular adaptation mechanisms.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid influences cell differentiation and growth, which might include the upregulation of PPIAL4F as part of its effects on cellular metabolism and protein synthesis.

Hydrogen Peroxide

7722-84-1sc-203336
sc-203336A
sc-203336B
100 ml
500 ml
3.8 L
$31.00
$61.00
$95.00
28
(1)

Hydrogen peroxide induces oxidative stress, potentially leading to an upregulation of PPIAL4F as part of the cellular antioxidant defense mechanisms.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin has anti-inflammatory and antioxidant effects, potentially modulating the expression of PPIAL4F as part of the cellular response to oxidative stress and inflammation.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate, an HDAC inhibitor, can lead to histone hyperacetylation, potentially affecting the expression of genes like PPIAL4F involved in protein folding and stress response.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin increases cAMP levels, potentially affecting PPIAL4F expression as part of cAMP-mediated cellular signaling pathways.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin, an mTOR inhibitor, affects cell growth and autophagy, which could indirectly influence PPIAL4F expression as part of the cellular response to altered growth conditions.