Date published: 2025-10-22

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PPAR alpha Activators

Santa Cruz Biotechnology now offers a broad range of PPAR alpha Activators for use in various applications. These activators specifically target peroxisome proliferator-activated receptor alpha (PPARα), a crucial nuclear receptor involved in the regulation of lipid metabolism, energy production, and inflammatory responses at a cellular level. PPAR alpha Activators are integral to scientific research exploring the mechanisms by which cells regulate fatty acid oxidation and maintain energy balance. These compounds enable researchers to artificially enhance PPARα activity, thereby studying its role in gene expression related to lipid processing and metabolic rate. Through the use of these activators, scientists gain insights into how PPARα influences cellular functions and systemic energy homeostasis, which is crucial for understanding metabolic processes in non-clinical research settings. The activators are also employed in examining the cross-talk between metabolic and inflammatory pathways, providing a detailed view of the interactions within cellular networks. This research is valuable for advancing our knowledge of cell biology and metabolism, focusing on how cellular energy processing impacts overall physiological functions. By providing these activators, Santa Cruz Biotechnology facilitates cutting-edge research that delves into fundamental aspects of cellular function and metabolic regulation, enhancing our understanding of critical biological processes. View detailed information on our available PPAR alpha Activators by clicking on the product name.

Items 11 to 20 of 44 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(S)-Ibuprofen

51146-56-6sc-200612
sc-200612A
1 g
5 g
$47.00
$140.00
4
(1)

(S)-Ibuprofen acts as a PPAR alpha modulator, exhibiting selective binding that influences lipid metabolism. Its unique stereochemistry enhances interactions with receptor sites, promoting the recruitment of transcription factors that regulate fatty acid oxidation. The compound's kinetic profile allows for precise modulation of metabolic pathways, while its structural features enable targeted activation of specific signaling networks, contributing to the intricate balance of energy homeostasis.

ETYA

1191-85-1sc-200764
sc-200764A
20 mg
100 mg
$75.00
$313.00
3
(1)

ETYA functions as a PPAR alpha modulator, characterized by its ability to engage in specific molecular interactions that influence gene expression related to lipid metabolism. Its unique structural attributes facilitate the formation of stable complexes with the receptor, enhancing the recruitment of coactivators. This compound exhibits distinct reaction kinetics, allowing for nuanced regulation of metabolic pathways, thereby impacting the dynamics of fatty acid utilization and energy balance.

Linoleic Acid

60-33-3sc-200788
sc-200788A
sc-200788B
sc-200788C
100 mg
1 g
5 g
25 g
$33.00
$63.00
$163.00
$275.00
4
(2)

Naturally occurring fatty acid that activates PPARα by binding.

Bezafibrate

41859-67-0sc-204650B
sc-204650
sc-204650A
sc-204650C
500 mg
1 g
5 g
10 g
$30.00
$45.00
$120.00
$200.00
5
(1)

Binds to PPARα to modulate lipid metabolism.

Oleoyl Ethanolamide-d4

946524-36-3sc-295976
sc-295976A
100 µg
500 µg
$32.00
$189.00
(0)

Oleoyl Ethanolamide-d4 acts as a PPAR alpha modulator, distinguished by its isotopic labeling that allows for precise tracking in metabolic studies. Its unique hydrophobic interactions promote effective binding to the receptor, influencing transcriptional activity. The compound's structural flexibility enables it to adapt within the receptor's binding pocket, optimizing the activation of downstream signaling pathways. This behavior contributes to the fine-tuning of lipid homeostasis and energy expenditure.

Oleic Acid

112-80-1sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$36.00
$102.00
$569.00
$1173.00
10
(1)

A fatty acid that can bind and activate PPARα.

8(S)-HETE

98462-03-4sc-200940
50 µg
$226.00
(0)

8(S)-HETE serves as a PPAR alpha ligand, characterized by its ability to engage in specific hydrogen bonding and hydrophobic interactions within the receptor's active site. This compound exhibits unique conformational dynamics, allowing it to stabilize receptor dimerization and enhance transcriptional regulation of target genes. Its role in modulating lipid metabolism is underscored by its influence on gene expression profiles, impacting cellular energy balance and fatty acid oxidation pathways.

AUDA

479413-70-2sc-221276
sc-221276A
5 mg
10 mg
$48.00
$82.00
1
(0)

AUDA acts as a PPAR alpha ligand, distinguished by its capacity to form unique electrostatic interactions and hydrophobic contacts within the receptor's binding pocket. This compound demonstrates notable conformational flexibility, facilitating the stabilization of receptor complexes and promoting downstream signaling cascades. Its influence extends to the modulation of metabolic pathways, particularly in lipid homeostasis, by altering the expression of genes involved in fatty acid metabolism and energy utilization.

Oleylethanolamide

111-58-0sc-201400
sc-201400A
10 mg
50 mg
$88.00
$190.00
1
(1)

Oleylethanolamide functions as a PPAR alpha agonist, characterized by its ability to engage in specific hydrogen bonding and hydrophobic interactions with the receptor. This compound exhibits a unique structural adaptability, allowing it to effectively stabilize receptor conformations and enhance transcriptional activity. Its role in regulating lipid metabolism is underscored by its impact on gene expression related to fatty acid oxidation and energy balance, influencing metabolic homeostasis.

Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3)

10417-94-4sc-200766
sc-200766A
100 mg
1 g
$102.00
$423.00
(0)

Long-chain polyunsaturated fatty acid that directly activates PPARα.