Potassium Channel Modulators
Items 41 to 50 of 103 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rose Bengal lactone | 4159-77-7 | sc-219991 | 1 g | $112.00 | ||
Rose Bengal lactone functions as a potassium channel modulator by engaging with the channel's lipid bilayer, altering its permeability to potassium ions. This compound exhibits unique photophysical properties, enabling it to induce conformational changes in the channel structure upon light activation. Its interactions can lead to distinct kinetic profiles, influencing the rate of ion conduction and channel inactivation, thereby affecting cellular membrane potential and excitability. | ||||||
Isopimaric Acid | 5835-26-7 | sc-269270 | 5 mg | $76.00 | 2 | |
Isopimaric Acid acts as a potassium channel modulator by selectively binding to specific sites within the channel's pore, influencing ion flow dynamics. Its unique structural features facilitate interactions with channel proteins, potentially stabilizing certain conformations that alter gating mechanisms. This compound exhibits distinct reaction kinetics, which can modulate the timing of channel activation and inactivation, thereby impacting cellular signaling pathways and ion homeostasis. | ||||||
Quinine hydrochloride dihydrate | 6119-47-7 | sc-212619 sc-212619A | 5 g 25 g | $63.00 $210.00 | ||
Quinine hydrochloride dihydrate functions as a potassium channel modulator by engaging in specific electrostatic interactions with channel residues, altering the conformational landscape of the protein. Its unique stereochemistry allows for selective binding, which can enhance or inhibit channel activity. The compound's solubility properties facilitate its diffusion across membranes, influencing the kinetics of ion transport and contributing to the modulation of cellular excitability and signaling cascades. | ||||||
Quinidine sulfate dihydrate | 6591-63-5 | sc-205967 | 5 g | $67.00 | ||
Quinidine sulfate dihydrate acts as a potassium channel modulator through its ability to stabilize specific channel conformations, impacting ion flow dynamics. Its unique structural features enable it to form hydrogen bonds and hydrophobic interactions with channel proteins, influencing gating mechanisms. The compound's dual solvation state enhances its interaction with lipid bilayers, affecting membrane permeability and ion selectivity, thereby modulating cellular electrical activity. | ||||||
Penitrem A | 12627-35-9 | sc-200997 sc-200997A | 1 mg 5 mg | $77.00 $216.00 | 5 | |
Penitrem A functions as a potassium channel modulator by selectively binding to channel sites, altering their conformational states and ion conductance. Its unique molecular structure allows for specific interactions with amino acid residues within the channel, influencing the kinetics of ion transport. Additionally, Penitrem A exhibits distinct electrostatic properties that enhance its affinity for channel proteins, thereby affecting the overall excitability of neuronal membranes and cellular signaling pathways. | ||||||
Tolfenamic Acid | 13710-19-5 | sc-204918 sc-204918A | 5 g 25 g | $69.00 $312.00 | ||
Tolfenamic Acid acts as a potassium channel modulator by engaging in specific interactions with channel proteins, leading to alterations in their gating mechanisms. Its unique structural features facilitate the stabilization of certain conformations, impacting ion flow dynamics. The compound's ability to form hydrogen bonds and hydrophobic interactions with channel residues enhances its modulatory effects, influencing cellular excitability and ion homeostasis in various biological systems. | ||||||
BL-1249 | 18200-13-0 | sc-252498 | 10 mg | $219.00 | ||
BL-1249 functions as a potassium channel modulator through its distinctive ability to selectively bind to specific sites on channel proteins, thereby influencing their conformational states. This compound exhibits unique electrostatic interactions that promote channel opening or closing, effectively altering ion permeability. Its kinetic profile reveals rapid binding and unbinding rates, allowing for fine-tuned modulation of ion currents, which can significantly impact cellular signaling pathways. | ||||||
Gliclazide | 21187-98-4 | sc-211561 | 1 g | $61.00 | 1 | |
Gliclazide acts as a potassium channel modulator by engaging in specific interactions with the channel's binding sites, leading to alterations in ion flow. Its unique structural features facilitate a dynamic equilibrium between open and closed states of the channel, enhancing or inhibiting ion conductance. The compound's reaction kinetics demonstrate a notable affinity for the channel, allowing for precise adjustments in cellular excitability and signaling dynamics. | ||||||
Glipizide | 29094-61-9 | sc-204768 sc-204768A | 1 g 5 g | $150.00 $612.00 | ||
Glipizide functions as a potassium channel modulator by selectively binding to the channel's regulatory sites, influencing the conformational states of the protein. This interaction stabilizes certain channel configurations, thereby modulating ion permeability. Its distinct molecular architecture promotes rapid kinetics, enabling swift transitions between activation and inactivation phases. This behavior contributes to nuanced control over cellular membrane potential and excitatory signaling pathways. | ||||||
Minoxidil (U-10858) | 38304-91-5 | sc-200984 sc-200984A | 100 mg 1 g | $68.00 $344.00 | ||
Minoxidil acts as a potassium channel modulator by interacting with specific binding sites on the channel, leading to alterations in its gating mechanisms. This interaction enhances the channel's conductance, facilitating potassium ion flow and influencing cellular excitability. Its unique structural features allow for a prolonged effect on channel activity, resulting in sustained modulation of electrical signaling. The compound's dynamic behavior in ion transport pathways underscores its role in fine-tuning cellular responses. | ||||||