Potassium Channel Modulators
Items 21 to 30 of 103 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quinine hemisulfate | 6119-70-6 | sc-202305 | 10 g | $51.00 | ||
Quinine hemisulfate functions as a potassium channel modulator through its ability to form hydrogen bonds and hydrophobic interactions with channel proteins. This compound stabilizes specific conformations, effectively altering ion flow. Its unique stereochemistry contributes to selective binding, influencing the kinetics of channel gating. Additionally, quinine hemisulfate's solubility characteristics facilitate its interaction with lipid membranes, impacting cellular excitability and signaling pathways. | ||||||
Quinidine hydrochloride monohydrate | 6151-40-2 | sc-215772 sc-215772A | 5 g 10 g | $66.00 $97.00 | ||
Quinidine hydrochloride monohydrate acts as a potassium channel modulator by engaging in specific electrostatic interactions with channel residues, which can lead to conformational changes in the protein structure. Its unique chiral centers enhance selectivity for certain potassium channels, affecting ion permeability and gating dynamics. The compound's solubility in aqueous environments promotes effective diffusion across membranes, influencing cellular ionic balance and excitability. | ||||||
Verruculogen | 12771-72-1 | sc-204939 sc-204939A | 1 mg 5 mg | $114.00 $284.00 | ||
Verruculogen functions as a potassium channel modulator through its ability to form hydrogen bonds and hydrophobic interactions with channel proteins, leading to altered gating mechanisms. Its unique structural features allow for selective binding to specific channel subtypes, impacting ion flow and channel kinetics. The compound's stability in various pH environments facilitates its interaction with membrane proteins, influencing cellular signaling pathways and excitability. | ||||||
U-37883A | 57568-80-6 | sc-201001 sc-201001A | 5 mg 25 mg | $79.00 $377.00 | 1 | |
U-37883A acts as a potassium channel modulator by engaging in specific electrostatic interactions with the channel's binding sites, which can lead to conformational changes in the protein structure. Its unique stereochemistry allows for preferential binding to certain channel isoforms, thereby fine-tuning ion conductance. Additionally, U-37883A exhibits a distinctive profile in reaction kinetics, influencing the rate of channel activation and inactivation, which can significantly affect cellular excitability and signaling dynamics. | ||||||
Docosahexaenoyl Ethanolamide | 162758-94-3 | sc-221563 sc-221563A sc-221563B | 5 mg 10 mg 50 mg | $70.00 $115.00 $580.00 | ||
Docosahexaenoyl Ethanolamide functions as a potassium channel modulator through its ability to stabilize specific channel conformations, enhancing or inhibiting ion flow. Its unique hydrophobic interactions with lipid bilayers facilitate selective channel gating, impacting ion permeability. The compound's distinct molecular flexibility allows it to adapt to various channel states, influencing the kinetics of activation and inactivation, thereby modulating cellular excitability and signaling pathways. | ||||||
NS 1643 | 448895-37-2 | sc-204135 sc-204135A | 10 mg 50 mg | $121.00 $464.00 | 3 | |
NS 1643 acts as a potassium channel modulator by selectively binding to specific channel sites, altering their conformational dynamics. This compound exhibits unique electrostatic interactions that influence the channel's gating mechanisms, promoting or reducing ion conductance. Its distinct structural features enable it to engage in rapid molecular rearrangements, affecting the kinetics of channel opening and closing, which can lead to nuanced changes in cellular ionic balance and signaling cascades. | ||||||
(−)-Bicuculline methiodide | 40709-69-1 | sc-200485 | 50 mg | $209.00 | 5 | |
(-)-Bicuculline methiodide functions as a potassium channel modulator by interacting with the channel's binding sites, leading to alterations in ion permeability. Its unique stereochemistry allows for specific interactions with channel proteins, influencing their activation thresholds. The compound's ability to stabilize certain conformations can modulate the kinetics of ion flow, resulting in intricate effects on cellular excitability and membrane potential dynamics. | ||||||
S-(+)-Niguldipine hydrochloride | 113165-32-5 | sc-203248 | 10 mg | $408.00 | 1 | |
S-(+)-Niguldipine hydrochloride acts as a potassium channel modulator by selectively binding to specific sites on the channel, thereby influencing gating mechanisms. Its unique chiral structure facilitates distinct interactions with the channel's protein matrix, altering ion conductance and influencing the channel's response to voltage changes. This compound exhibits a nuanced effect on the kinetics of ion transport, contributing to the regulation of cellular ionic homeostasis and excitability. | ||||||
PCO 400 | 121055-10-5 | sc-200989 sc-200989A | 20 mg 100 mg | $61.00 $217.00 | 2 | |
PCO 400 functions as a potassium channel modulator through its ability to interact with the channel's lipid bilayer, enhancing membrane fluidity and altering channel conformation. Its unique structural features promote specific hydrogen bonding and hydrophobic interactions, which fine-tune the channel's activation threshold. This compound exhibits a distinctive influence on the kinetics of ion flux, impacting the overall electrochemical gradient and cellular signaling pathways. | ||||||
SK&F 96365 | 130495-35-1 | sc-201475 sc-201475B sc-201475A sc-201475C | 5 mg 10 mg 25 mg 50 mg | $101.00 $155.00 $389.00 $643.00 | 2 | |
SK&F 96365 acts as a potassium channel modulator by selectively binding to specific sites within the channel's pore, leading to conformational changes that affect ion permeability. Its unique molecular structure facilitates interactions with key amino acid residues, influencing gating mechanisms. This compound also alters the kinetics of ion transport, thereby modulating the electrochemical gradients across membranes and affecting cellular excitability and signaling dynamics. | ||||||