PLUNC Inhibitors
PLUNC, which stands for Palate, Lung, and Nasal Epithelium Clone protein, is a group of proteins primarily expressed in the respiratory and upper airway epithelial tissues. These proteins are known for their roles in innate immunity and mucosal defense against microbial infections. PLUNC proteins are involved in various immune responses, including the regulation of inflammation, the clearance of pathogens, and the maintenance of airway hydration.
PLUNC inhibitors are designed to target and modulate the activity of PLUNC proteins, potentially interfering with their roles in innate immunity and mucosal defense. By inhibiting specific PLUNC proteins, these compounds may impact the host's ability to respond to respiratory infections and maintain airway homeostasis. Researchers employ PLUNC inhibitors as valuable tools to investigate the specific functions and regulatory mechanisms of PLUNC proteins in different cellular contexts, particularly within the respiratory system.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can reactivate genes silenced by methylation, potentially altering PLUNC expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
An active diterpenoid epoxide that may affect transcription factors and inflammatory pathways, possibly downregulating PLUNC expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
A compound in cruciferous vegetables that acts as a histone deacetylase inhibitor, potentially altering gene expression including PLUNC. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid that can regulate inflammation and immune responses, potentially decreasing PLUNC expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A catechin found in green tea, known for modulating numerous cellular pathways, potentially affecting PLUNC expression. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
A flavonoid with various biological effects, which might include the modulation of genes involved in inflammation and immunity. | ||||||
Vitamin A | 68-26-8 | sc-280187 sc-280187A | 1 g 10 g | $377.00 $2602.00 | ||
A form of vitamin A that regulates gene expression through retinoic acid receptors and may affect PLUNC production. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Found in cruciferous vegetables, it can modulate estrogen metabolism and potentially influence immune-related gene expression. | ||||||
β-Catenin/Tcf Inhibitor, FH535 | 108409-83-2 | sc-221398 sc-221398A | 10 mg 50 mg | $178.00 $367.00 | 7 | |
A compound that inhibits Wnt/β-catenin signaling, which may have effects on immune response gene regulation. | ||||||