PLIC-1 Activators
The chemical class termed PLIC-1 Activators encompasses compounds with the capability to indirectly modulate the activity of the PLIC-1 (UBQLN1) protein. These compounds are varied and function through diverse mechanisms, affecting the protein by modulating related cellular pathways or processes, such as cellular differentiation, stress response, and intracellular signaling cascades. Dexamethasone, for instance, can influence various cellular processes and pathways due to its glucocorticoid properties. Retinoic Acid, on the other hand, is known to play a crucial role in cellular differentiation and may, thereby, have an indirect effect on PLIC-1 activity. Another example is Lithium Chloride, which by influencing the Wnt signaling pathway, can have a secondary effect on PLIC-1 activity.
In addition to these, several other chemicals like Forskolin, PD98059, and LY294002 operate through distinct mechanisms, impacting different intracellular signaling pathways and cellular components. Forskolin activates adenylyl cyclase and can influence various intracellular signaling cascades. PD98059 inhibits MEK, possibly influencing PLIC-1 through alterations in ERK signaling pathways. LY294002 is a PI3K inhibitor and can possibly influence PLIC-1 indirectly through alterations in AKT signaling.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Glucocorticoid, possibly affecting PLIC-1 activity indirectly through various cellular processes. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences cellular differentiation, possibly having an indirect effect on PLIC-1 activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences Wnt signaling pathway, might have a secondary effect on PLIC-1 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Influences intracellular signaling cascades, potentially impacting PLIC-1 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, possibly influencing PLIC-1 indirectly through ERK signaling. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Impacts PLIC-1 indirectly through alterations in cellular cytoskeleton dynamics. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Influences PLIC-1 activity indirectly through alterations in cellular stress response. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
Might have secondary effects on PLIC-1 by inhibiting Ca2+/calmodulin-dependent protein kinase II. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Possibly influences PLIC-1 indirectly through alterations in AKT signaling by inhibiting PI3K. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Influences PLIC-1 through alterations in cellular growth and proliferation by inhibiting mTOR. | ||||||