Date published: 2025-9-25

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Phospholipids

Santa Cruz Biotechnology now offers a broad range of phospholipids for use in various applications. Phospholipids, essential components of cell membranes, consist of two fatty acid tails and a phosphate group attached to a glycerol backbone. Their amphipathic nature, with hydrophilic heads and hydrophobic tails, makes them crucial in the formation of lipid bilayers, which are fundamental to cell structure and function. In scientific research, phospholipids are extensively used to study membrane dynamics, protein-lipid interactions, and cell signaling pathways. They are vital in the investigation of membrane fluidity and permeability, as well as in the development of model membrane systems such as liposomes and nanodiscs, which are used for drug delivery, biochemical assays, and structural biology studies. Environmental scientists use phospholipids as biomarkers to assess microbial community structure and function in various ecosystems. In analytical chemistry, phospholipids are key in techniques like mass spectrometry and chromatography, aiding in the identification and quantification of lipid species in complex biological samples. Additionally, phospholipids play a role in materials science, where their unique properties are harnessed to develop advanced materials and nanotechnologies. The broad applicability of phospholipids across multiple disciplines underscores their importance in advancing our understanding of biological processes and in the development of innovative technologies. View detailed information on our available phospholipids by clicking on the product name.

Items 1 to 10 of 176 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lysophosphatidic Acid

325465-93-8sc-201053
sc-201053A
5 mg
25 mg
$96.00
$334.00
50
(3)

Lysophosphatidic Acid is a bioactive phospholipid known for its role in cellular signaling and membrane dynamics. Its unique structure allows for specific interactions with membrane proteins, influencing cellular processes such as proliferation and migration. The compound exhibits amphiphilic properties, enabling it to form micelles and interact with lipid bilayers. Additionally, it participates in various signaling pathways, modulating intracellular calcium levels and activating specific kinases, thereby impacting cellular responses.

Calyculin A

101932-71-2sc-24000
sc-24000A
sc-24000B
sc-24000C
10 µg
100 µg
500 µg
1 mg
$160.00
$750.00
$1400.00
$3000.00
59
(3)

Calyculin A is a potent phospholipid that acts as a selective inhibitor of protein phosphatases, influencing cellular signaling cascades. Its unique ability to bind to the active sites of phosphatases alters phosphorylation states of proteins, thereby modulating various cellular functions. The compound's structural features facilitate strong interactions with lipid membranes, enhancing its stability and bioavailability. This interaction can lead to significant changes in membrane fluidity and organization, impacting cellular dynamics.

Geranylgeranylpyrophosphate triammonium salt

6699-20-3sc-200849
200 µg
$120.00
(1)

Geranylgeranylpyrophosphate triammonium salt is a key phospholipid that plays a crucial role in cellular signaling and membrane dynamics. Its unique structure allows for effective interactions with membrane proteins, influencing lipid bilayer integrity and fluidity. The compound participates in distinct biosynthetic pathways, particularly in the prenylation of proteins, which is essential for their proper localization and function. Its reactivity with various biomolecules highlights its importance in cellular processes.

3-sn-Phosphatidylethanolamine

90989-93-8sc-231925
5 mg
$61.00
(1)

3-sn-Phosphatidylethanolamine is a vital phospholipid that contributes significantly to membrane structure and function. Its amphipathic nature facilitates the formation of lipid bilayers, promoting membrane curvature and fusion. This phospholipid is involved in critical cellular processes, including membrane trafficking and signal transduction. Additionally, it serves as a precursor for bioactive molecules, influencing various metabolic pathways and cellular responses through its unique interactions with proteins and other lipids.

Sphingomyelin

85187-10-6sc-201381
sc-201381A
100 mg
500 mg
$163.00
$520.00
3
(1)

Sphingomyelin is a unique phospholipid characterized by its sphingosine backbone and fatty acid chains, which contribute to its distinct structural properties. It plays a crucial role in membrane stability and fluidity, influencing lipid raft formation and cellular signaling. Sphingomyelin's interactions with cholesterol enhance membrane integrity, while its metabolism generates bioactive sphingolipids that modulate cellular responses. This phospholipid is integral to neuronal function and myelin sheath formation, showcasing its importance in cellular architecture.

D-erythro-Sphingosine-1-phosphate

26993-30-6sc-201383
sc-201383D
sc-201383A
sc-201383B
sc-201383C
1 mg
2 mg
5 mg
10 mg
25 mg
$162.00
$316.00
$559.00
$889.00
$1693.00
7
(1)

D-erythro-Sphingosine-1-phosphate is a bioactive sphingolipid that serves as a signaling molecule within cellular membranes. Its unique structure allows for specific interactions with G-protein coupled receptors, influencing various intracellular pathways. This compound is involved in regulating cell proliferation, migration, and survival, highlighting its role in cellular communication. Additionally, it modulates ion channel activity and contributes to the maintenance of cellular homeostasis, showcasing its dynamic behavior in lipid bilayers.

HNMPA-(AM)3

120944-03-8sc-221730
5 mg
$186.00
12
(1)

HNMPA-(AM)3 is a phospholipid characterized by its amphiphilic nature, which facilitates the formation of stable lipid bilayers. Its unique headgroup structure enhances molecular interactions with proteins, promoting membrane fluidity and flexibility. This compound exhibits distinct reaction kinetics, allowing for rapid incorporation into cellular membranes. Additionally, it plays a crucial role in membrane fusion processes, influencing vesicle trafficking and cellular compartmentalization.

1-Oleoyl lysophosphatidic acid

65528-98-5sc-222720
sc-222720A
sc-222720B
sc-222720C
1 mg
5 mg
10 mg
25 mg
$31.00
$139.00
$245.00
$530.00
11
(1)

1-Oleoyl lysophosphatidic acid is a phospholipid distinguished by its unsaturated fatty acid tail, which contributes to its fluidity and dynamic behavior in lipid environments. This compound engages in specific molecular interactions with membrane proteins, modulating signaling pathways and influencing cellular responses. Its unique structure allows for rapid lateral diffusion within membranes, enhancing membrane organization and facilitating lipid raft formation, which is essential for cellular communication.

Phosphatidic Acid, Dioleoyl

108392-02-5sc-201059
10 mg
$250.00
1
(1)

Dioleoyl phosphatidic acid is a phospholipid characterized by its two oleoyl chains, which impart significant flexibility and fluidity to lipid bilayers. This compound plays a crucial role in membrane dynamics, promoting the formation of lipid domains and influencing membrane curvature. Its ability to interact with various proteins and lipids facilitates critical cellular processes, including vesicle trafficking and membrane fusion, thereby impacting cellular architecture and function.

KOdiA-PC

439904-33-3sc-224033
sc-224033A
sc-224033B
sc-224033C
500 µg
1 mg
50 mg
100 mg
$82.00
$155.00
$5610.00
$10200.00
(0)

KOdiA-PC is a phospholipid distinguished by its unique amphiphilic structure, which enables it to form stable micelles and lipid bilayers. Its hydrophilic head group enhances solubility in aqueous environments, while the hydrophobic tails contribute to membrane integrity. This compound exhibits specific interactions with membrane proteins, modulating their activity and influencing signal transduction pathways. Additionally, KOdiA-PC's dynamic behavior under varying conditions allows for adaptability in cellular environments.