Date published: 2026-5-16

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KOdiA-PC (CAS 439904-33-3)

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Alternate Names:
1-(Palmitoyl)-2-(5-keto-6-octene-dioyl) phosphatidylcholine
Application:
KOdiA-PC is one of the most potent CD36 ligands
CAS Number:
439904-33-3
Molecular Weight:
663.77
Molecular Formula:
C32H58NO11P
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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KOdiA-PC, also known as 1-O-hexadecyl-2-O-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine, is a chemical compound that has been extensively studied in scientific research, particularly in the field of lipidomics and membrane biology. It serves as an important tool for investigating lipid metabolism and cellular signaling processes. KOdiA-PC is a synthetic phospholipid derivative that mimics the structure of natural phospholipids found in cell membranes. It has been utilized to explore the dynamics and functions of phospholipids in cellular membranes. Researchers have investigated the incorporation and metabolism of KOdiA-PC in cells, examining its interactions with enzymes and proteins involved in phospholipid synthesis, remodeling, and degradation. Moreover, KOdiA-PC has been employed to study lipid-protein interactions, membrane fusion events, and the role of phospholipids in membrane organization and function. By manipulating the levels or ratios of specific lipid species, researchers can gain insights into the roles of phospholipids in cellular processes such as membrane trafficking, cellular signaling, and lipid homeostasis. The study of KOdiA-PC contributes to advancements in understanding the complex mechanisms of lipid metabolism and the roles of phospholipids in cellular physiology. This research has implications for various research applications related to lipidomics, membrane biology, and cellular signaling pathways.


KOdiA-PC (CAS 439904-33-3) References

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  2. Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36.  |  Podrez, EA., et al. 2002. J Biol Chem. 277: 38503-16. PMID: 12105195
  3. A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.  |  Podrez, EA., et al. 2002. J Biol Chem. 277: 38517-23. PMID: 12145296
  4. Mapping and characterization of the binding site for specific oxidized phospholipids and oxidized low density lipoprotein of scavenger receptor CD36.  |  Kar, NS., et al. 2008. J Biol Chem. 283: 8765-71. PMID: 18245080
  5. Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters.  |  Ashraf, MZ., et al. 2008. J Biol Chem. 283: 10408-14. PMID: 18285332
  6. Structural basis for the recognition of oxidized phospholipids in oxidized low density lipoproteins by class B scavenger receptors CD36 and SR-BI.  |  Gao, D., et al. 2010. J Biol Chem. 285: 4447-54. PMID: 19996318
  7. Closely related oxidized phospholipids differentially modulate the physicochemical properties of lipid particles.  |  Kar, S., et al. 2011. Chem Phys Lipids. 164: 54-61. PMID: 21074521
  8. A synthetic peptide-based assay system for detecting binding between CD36 and an oxidized low-density lipoprotein.  |  Tsuzuki, S., et al. 2013. Biosci Biotechnol Biochem. 77: 132-7. PMID: 23291771
  9. Analysis of relationship between oxidized phospholipid structure and interaction with the class B scavenger receptors.  |  Gao, D., et al. 2015. Methods Mol Biol. 1208: 29-48. PMID: 25323497
  10. CHARMM GUI Membrane Builder for oxidized phospholipid membrane modeling and simulation.  |  Brown, TP., et al. 2024. Curr Opin Struct Biol. 86: 102813. PMID: 38598982

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

KOdiA-PC, 500 µg

sc-224033
500 µg
$84.00

KOdiA-PC, 1 mg

sc-224033A
1 mg
$158.00

KOdiA-PC, 50 mg

sc-224033B
50 mg
$5722.00

KOdiA-PC, 100 mg

sc-224033C
100 mg
$10404.00