The chemical class referred to as PGBD2 Activators constitutes a specific group of compounds recognized for their ability to modulate the activity of the PGBD2 gene. PGBD2, or PiggyBac Transposable Element Derived 2, is a gene encoding a protein that belongs to the PiggyBac transposase family. Transposases are enzymes responsible for catalyzing the movement of transposable elements within the genome, which can lead to genetic rearrangements and alterations. While the exact function of PGBD2 is not fully elucidated, it is believed to play a role in mediating DNA rearrangements and possibly contributing to genomic plasticity and evolution. Activators of PGBD2 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.
Characterizing compounds as PGBD2 Activators usually involves comprehensive screening processes aimed at evaluating their ability to interact with regulatory elements of the PGBD2 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for PGBD2 gene expression, or modulating post-translational modifications of the PGBD2 protein. Understanding the molecular mechanisms underlying PGBD2 activation by these compounds is crucial for elucidating the roles of PGBD2 in genome dynamics and evolution. Further research into PGBD2 Activators may provide insights into novel cellular pathways and contribute to a deeper understanding of PGBD2's function in genome regulation and genetic diversity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A green tea polyphenol that may influence epigenetic mechanisms and gene expression through modulation of DNA methylation and histone modification. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
An isoflavone that may act as an epigenetic modulator, potentially affecting the transcription of a range of genes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that could lead to changes in chromatin structure and subsequently influence gene transcription. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A nucleoside analog that inhibits DNA methyltransferase, potentially leading to hypomethylation of DNA and altered gene expression. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
An inhibitor of histone methyltransferase EZH2, which may lead to changes in histone methylation and gene expression. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
May alter the activity of various metalloenzymes and transcription factors, influencing gene transcription indirectly. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A histone deacetylase inhibitor that can affect gene expression by altering chromatin accessibility. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
An antioxidant that can also act as a cofactor for dioxygenase enzymes, potentially influencing DNA demethylation and gene expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase inhibitor that can change chromatin dynamics and potentially affect gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
An agent that binds to DNA and may influence transcription factor binding and gene expression. | ||||||