Date published: 2026-1-9

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PAR-2 Antibodies

Santa Cruz Biotechnology features a diverse variety of PAR-2 monoclonal antibodies for research focused on understanding protease-activated receptor 2 (PAR-2) in various biological processes. PAR-2 monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).PAR-2 is a G protein-coupled receptor that plays a critical role in mediating inflammatory responses and pain signaling. When activated by proteolytic cleavage, PAR-2 initiates a cascade of intracellular signaling events that influence cell behavior and tissue homeostasis. Understanding PAR-2 function is essential for elucidating its involvement in various pathophysiological conditions, including chronic pain, inflammation, and cancer. Research has shown that PAR-2 expression levels vary significantly across different tissue types and disease states. PAR-2 signaling pathways have emerged as potential therapeutic targets for treating inflammatory disorders. Recent studies have highlighted PAR-2's role in neurogenic inflammation and its potential implications in developing new treatment strategies. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance their understanding of PAR-2's role in human health and disease.

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PAR-2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PAR-2 Antibody (SAM11)

sc-13504mouse IgG2a κ37-50 (h)WB, IP, IF, IHC(P), FCMm, r, h
262
(10)

PAR-2 Antibody (3G233)

sc-71842mouse IgG2a κ37-50 (h)WB, IP, IF, FCMm, r, h
1
(1)

PAR-2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAR-2 CRISPR/Cas9 KO Plasmid (h)

sc-400333hGene KnockoutGFP0
(0)

PAR-2 HDR Plasmid (h)

sc-400333-HDRhHomology Directed RepairPuromycin0
(0)

PAR-2 Double Nickase Plasmid (h)

sc-400333-NIChGene KnockoutPuromycin0
(0)

PAR-2 Double Nickase Plasmid (h2)

sc-400333-NIC-2hGene KnockoutPuromycin0
(0)

PAR-2 CRISPR/Cas9 KO Plasmid (m2)

sc-420265-KO-2mGene KnockoutGFP0
(0)

PAR-2 HDR Plasmid (m2)

sc-420265-HDR-2mHomology Directed RepairPuromycin0
(0)

PAR-2 Double Nickase Plasmid (m)

sc-420265-NICmGene KnockoutPuromycin0
(0)

PAR-2 Double Nickase Plasmid (m2)

sc-420265-NIC-2mGene KnockoutPuromycin0
(0)

PAR-2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAR-2 CRISPR Activation Plasmid (h)

sc-400333-ACThGene ActivationPuro, Blast, Hygro0
(0)

PAR-2 CRISPR Activation Plasmid (h2)

sc-400333-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PAR-2 Lentiviral Activation Particles (h)

sc-400333-LAChGene ActivationPuro, Blast, Hygro0
(0)

PAR-2 Lentiviral Activation Particles (h2)

sc-400333-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PAR-2 CRISPR Activation Plasmid (m)

sc-420265-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAR-2 CRISPR Activation Plasmid (m2)

sc-420265-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAR-2 Lentiviral Activation Particles (m)

sc-420265-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAR-2 Lentiviral Activation Particles (m2)

sc-420265-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAR-2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PAR-2 siRNA (h)

sc-36188hGene SilencingN/A
33
(0)

PAR-2 shRNA Plasmid (h)

sc-36188-SHhGene SilencingPuromycin
33
(0)

PAR-2 shRNA (h) Lentiviral Particles

sc-36188-VhGene SilencingPuromycin
33
(0)

PAR-2 siRNA (m)

sc-36187mGene SilencingN/A
2
(0)

PAR-2 shRNA Plasmid (m)

sc-36187-SHmGene SilencingPuromycin
2
(0)

PAR-2 shRNA (m) Lentiviral Particles

sc-36187-VmGene SilencingPuromycin
2
(0)

PAR-2 siRNA (r)

sc-156080rGene SilencingN/A
1
(0)

PAR-2 shRNA Plasmid (r)

sc-156080-SHrGene SilencingPuromycin
1
(0)

PAR-2 shRNA (r) Lentiviral Particles

sc-156080-VrGene SilencingPuromycin
1
(0)