Pan-Acetyl Activators belong to a distinct chemical class of compounds that have garnered considerable attention in the realm of cellular and molecular biology. These molecules are recognized for their ability to modulate protein acetylation, a crucial post-translational modification process. Acetylation involves the attachment of acetyl groups to proteins, which can profoundly impact their structure and function. Pan-Acetyl Activators are particularly notable because they possess the capacity to influence protein acetylation on a broad scale, affecting a diverse array of proteins within cells.
These activators typically function by either promoting the acetylation of specific lysine residues on target proteins or inhibiting the deacetylation process, often mediated by enzymes such as histone deacetylases (HDACs). By altering protein acetylation, Pan-Acetyl Activators can impact various fundamental cellular processes, including gene expression, cell cycle regulation, DNA repair, and protein stability. In laboratory settings, researchers frequently employ these compounds as invaluable tools to delve into the intricate mechanisms governing epigenetic regulation and post-translational modifications.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This compound is a potent histone deacetylase inhibitor which can lead to increased acetylation levels of histones and other proteins. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As a histone deacetylase inhibitor, it can cause an increase in acetylated proteins within the cell. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Approved as an HDAC inhibitor, Suberoylanilide Hydroxamic Acid increases acetylation of histone proteins. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has been reported to inhibit HDAC activity, which might result in enhanced acetylation of proteins. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
As a part of its multiple biological effects, resveratrol has been shown to modulate histone acetylation levels. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $136.00 $492.00 | 13 | |
Garcinol is known to inhibit histone acetyltransferases, potentially affecting acetylation patterns. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $100.00 $200.00 | 13 | |
This compound is a histone acetyltransferase inhibitor, potentially altering acetylation status of proteins. | ||||||
Sirtinol | 410536-97-9 | sc-205976 sc-205976A | 1 mg 5 mg | $37.00 $111.00 | 14 | |
As an inhibitor of sirtuin deacetylases, sirtinol can increase the acetylation of proteins. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
It has potential effects on histone acetylation through modulation of HDAC activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG has been shown to affect HDAC and HAT activities, influencing acetylation patterns. |