Date published: 2025-10-10

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pan-Acetyl Activators

Pan-Acetyl Activators belong to a distinct chemical class of compounds that have garnered considerable attention in the realm of cellular and molecular biology. These molecules are recognized for their ability to modulate protein acetylation, a crucial post-translational modification process. Acetylation involves the attachment of acetyl groups to proteins, which can profoundly impact their structure and function. Pan-Acetyl Activators are particularly notable because they possess the capacity to influence protein acetylation on a broad scale, affecting a diverse array of proteins within cells.

These activators typically function by either promoting the acetylation of specific lysine residues on target proteins or inhibiting the deacetylation process, often mediated by enzymes such as histone deacetylases (HDACs). By altering protein acetylation, Pan-Acetyl Activators can impact various fundamental cellular processes, including gene expression, cell cycle regulation, DNA repair, and protein stability. In laboratory settings, researchers frequently employ these compounds as invaluable tools to delve into the intricate mechanisms governing epigenetic regulation and post-translational modifications.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

This compound is a potent histone deacetylase inhibitor which can lead to increased acetylation levels of histones and other proteins.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

As a histone deacetylase inhibitor, it can cause an increase in acetylated proteins within the cell.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Approved as an HDAC inhibitor, Suberoylanilide Hydroxamic Acid increases acetylation of histone proteins.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin has been reported to inhibit HDAC activity, which might result in enhanced acetylation of proteins.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

As a part of its multiple biological effects, resveratrol has been shown to modulate histone acetylation levels.

Garcinol

78824-30-3sc-200891
sc-200891A
10 mg
50 mg
$136.00
$492.00
13
(1)

Garcinol is known to inhibit histone acetyltransferases, potentially affecting acetylation patterns.

Anacardic Acid

16611-84-0sc-202463
sc-202463A
5 mg
25 mg
$100.00
$200.00
13
(1)

This compound is a histone acetyltransferase inhibitor, potentially altering acetylation status of proteins.

Sirtinol

410536-97-9sc-205976
sc-205976A
1 mg
5 mg
$37.00
$111.00
14
(1)

As an inhibitor of sirtuin deacetylases, sirtinol can increase the acetylation of proteins.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

It has potential effects on histone acetylation through modulation of HDAC activity.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG has been shown to affect HDAC and HAT activities, influencing acetylation patterns.