PAF-R Activators
SEE ALSO...
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ET-18-OCH3 | 77286-66-9 | sc-201021 sc-201021A sc-201021B sc-201021C sc-201021F | 5 mg 25 mg 50 mg 100 mg 1 g | $109.00 $427.00 $826.00 $1545.00 $3682.00 | 6 | |
ET-18-OCH3 functions as a potent PAF receptor antagonist, exhibiting unique molecular interactions that disrupt the binding of platelet-activating factor. Its structural conformation allows for effective competition at the receptor site, altering downstream signaling pathways. The compound's hydrophobic characteristics enhance its affinity for lipid membranes, influencing membrane fluidity and receptor accessibility, which can significantly affect cellular responses in various biological contexts. | ||||||
C-PAF (Carbamyl-PAF ) | 91575-58-5 | sc-201025 | 5 mg | $370.00 | 3 | |
C-PAF, a carbamyl derivative of platelet-activating factor, exhibits distinctive interactions with PAF receptors, characterized by its ability to form stable hydrogen bonds and hydrophobic contacts. This compound influences receptor conformation, modulating signal transduction pathways. Its unique steric properties facilitate selective binding, while its reactivity as an acid halide allows for rapid participation in nucleophilic substitution reactions, impacting cellular signaling dynamics. | ||||||
PAF C-16 | 74389-68-7 | sc-201009 sc-201009A | 5 mg 25 mg | $128.00 $294.00 | 10 | |
PAF C-16, a potent PAF receptor agonist, showcases remarkable molecular interactions through its unique carbon chain, enhancing lipid bilayer integration. Its structural configuration promotes specific binding affinities, leading to altered receptor dynamics. The compound's reactivity as an acid halide enables efficient acylation processes, influencing downstream signaling cascades. Additionally, its hydrophobic characteristics contribute to membrane permeability, affecting cellular uptake and response mechanisms. | ||||||
2-O-methyl PAF C-16 | 78858-44-3 | sc-205087 sc-205087A | 5 mg 10 mg | $50.00 $174.00 | ||
2-O-methyl PAF C-16 acts as a selective PAF receptor modulator, distinguished by its unique ether linkage that enhances its stability and bioavailability. This compound exhibits specific interactions with lipid membranes, facilitating its incorporation into cellular structures. Its reactivity as an acid halide allows for targeted acylation, influencing protein interactions and signal transduction pathways. The compound's hydrophobic nature further enhances its affinity for membrane-associated proteins, impacting cellular signaling dynamics. | ||||||
WEB-2086 | 105219-56-5 | sc-201007 sc-201007A | 1 mg 5 mg | $100.00 $163.00 | 13 | |
WEB 2086 is a PAF-R antagonist that indirectly activates PAF-R. By blocking the inhibitory effect of endogenous PAF, it enhances PAF-R signaling. This results in increased PAF-R activation and downstream cellular responses. | ||||||
PAF C-18:1 | 85966-90-1 | sc-201019 sc-201019A | 5 mg 25 mg | $80.00 $345.00 | 1 | |
PAF C-18:1 functions as a potent PAF receptor agonist, characterized by its long acyl chain that promotes enhanced membrane fluidity and interaction with lipid bilayers. This compound exhibits unique binding kinetics, allowing for rapid receptor activation and subsequent downstream signaling. Its structural features facilitate specific molecular interactions, influencing cellular responses and modulating inflammatory pathways. The compound's amphipathic nature aids in its integration into lipid environments, affecting membrane dynamics and receptor accessibility. | ||||||
2-O-ethyl PAF C-16 | 78858-42-1 | sc-220757 sc-220757A | 5 mg 10 mg | $113.00 $220.00 | ||
2-O-ethyl PAF C-16 acts as a selective PAF receptor modulator, distinguished by its shorter acyl chain, which influences its interaction with lipid membranes. This compound exhibits unique conformational flexibility, allowing it to engage in specific hydrogen bonding and hydrophobic interactions with receptor sites. Its rapid diffusion through lipid bilayers enhances its bioavailability, while its distinct molecular structure alters receptor conformations, impacting signal transduction pathways and cellular responses. | ||||||
Rupatadine Fumarate | 182349-12-8 | sc-212795 | 10 mg | $200.00 | ||
Rupatadine is an antagonist of histamine receptors, and it indirectly activates PAF-R by inhibiting histamine-induced downregulation of PAF-R. This leads to enhanced PAF-R signaling and cellular responses. | ||||||
Lyso-PAF (C18) | 74430-89-0 | sc-203123 sc-203123A | 1 mg 25 mg | $56.00 $342.00 | ||
Lyso-PAF (C18) functions as a potent PAF receptor antagonist, characterized by its elongated acyl chain that enhances its affinity for lipid bilayers. This compound exhibits unique electrostatic interactions, facilitating its binding to receptor sites and modulating downstream signaling cascades. Its ability to form stable complexes with membrane proteins influences cellular dynamics, while its kinetic profile allows for swift receptor engagement, altering physiological responses effectively. | ||||||
PAF C-16-d4 | 211106-54-6 | sc-224198 sc-224198A | 100 µg 500 µg | $30.00 $124.00 | ||
PAF C-16-d4 acts as a selective PAF receptor modulator, distinguished by its deuterated acyl chain that alters isotopic labeling and enhances stability in biological systems. This compound exhibits unique hydrophobic interactions, promoting its integration into lipid membranes. Its distinct reaction kinetics enable rapid receptor binding and dissociation, influencing cellular signaling pathways. Additionally, the presence of deuterium may affect metabolic stability, providing insights into molecular behavior in various environments. | ||||||