PABP Inhibitors
Common PABP Inhibitors include, but are not limited to Cordycepin CAS 73-03-0, Aurintricarboxylic Acid CAS 4431-00-9, C646 CAS 328968-36-1, CCG-1423 CAS 285986-88-1 and Ribavirin CAS 36791-04-5.
PABP inhibitors are a group of chemical compounds designed to interact with the poly(A)-binding protein (PABP). This protein, also known as PABPC1, plays a pivotal role in mRNA metabolism and translation regulation. PABP binds to the poly(A) tail of mRNA molecules, thereby influencing their stability, translation efficiency, and cellular localization. Inhibitors targeting PABP are meticulously designed to interact with specific binding sites within the protein's structure, with the aim of modulating its ability to interact with mRNA molecules.
The interaction between PABP inhibitors and the PABP protein holds the ability to offer novel insights into the intricate mechanisms underlying post-transcriptional gene regulation and protein synthesis. By selectively influencing the interaction between PABP and mRNA, these inhibitors provide a tool to explore how alterations in this interaction affect gene expression and cellular processes. The exploration of PABP inhibitors contributes to a deeper understanding of the molecular processes that govern mRNA metabolism, translation, and cellular responses to various stimuli. This class of inhibitors contributes to the advancement of our knowledge regarding the regulation of gene expression and the intricate interplay between mRNA processing, translation, and cellular homeostasis.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Cordycepin might inhibit PABP indirectly by affecting mRNA stability and translation through interference with polyadenylation. | ||||||
A-485 | 1889279-16-6 | sc-507493 | 5 mg | $275.00 | ||
A-485 is a selective inhibitor of PABPC1, a member of the PABP family, potentially impacting mRNA translation and stability. | ||||||
Aurintricarboxylic Acid | 4431-00-9 | sc-3525 sc-3525A sc-3525B sc-3525C | 100 mg 1 g 5 g 10 g | $20.00 $32.00 $48.00 $94.00 | 13 | |
Aurintricarboxylic acid might interfere with PABP binding to mRNA, potentially affecting mRNA stability and translation. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
C646 is a histone acetyltransferase inhibitor that might affect PABP indirectly through its impact on gene expression and mRNA stability. | ||||||
CCG-1423 | 285986-88-1 | sc-205241 sc-205241A | 1 mg 5 mg | $30.00 $90.00 | 8 | |
CCG-1423 is a Rho pathway inhibitor that might indirectly impact PABP through its effects on cytoskeletal dynamics and mRNA transport. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $63.00 $110.00 $214.00 | 1 | |
Ribavirin might indirectly impact PABP by affecting mRNA stability and translation, particularly in the context of viral infections. | ||||||
Chitosan | 9012-76-4 | sc-221421 sc-221421A sc-221421B sc-221421D sc-221421C | 10 g 25 g 100 g 8 kg 500 g | $41.00 $55.00 $135.00 $3339.00 $298.00 | 6 | |
Chitosan might indirectly impact PABP by affecting mRNA stability and translation through its interactions with nucleic acids. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $27.00 $35.00 | 20 | |
Neomycin might affect PABP indirectly by interfering with RNA structure and interactions, potentially impacting mRNA translation and stability. | ||||||