Date published: 2025-10-8

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p300 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of p300 monoclonal antibodies for investigating p300 protein activity in various cellular processes. The monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). p300 protein functions as a crucial co-activator in gene expression regulation, playing a significant role in cellular signaling pathways and transcriptional activation. Its activity is essential in processes such as cell growth, differentiation, and response to external stimuli, making p300 an important target for research in cancer and other diseases. Understanding p300 mechanisms can provide insights into therapeutic strategies and the development of targeted treatments. Researchers worldwide rely on p300 monoclonal antibodies to advance their studies in cell biology, cancer research, and drug development. p300 monoclonal antibodies enable reproducible results across multiple experimental applications. Santa Cruz Biotechnology monoclonal antibodies for p300 continue to support breakthrough discoveries in cellular and molecular biology research.

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p300 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p300 Antibody (F-4)

sc-48343mouse IgG2a κ774-1045 (h)WB, IP, IF, IHC(P), ELISAm, r, h
103
(40)

p300 Antibody (NM11)

sc-32244mouse IgG2b κ2071-2091 (h)WB, IP, IF, IHC(P)m, r, h
49
(14)

p300 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

p300 CRISPR/Cas9 KO Plasmid (h)

sc-400055hGene KnockoutGFP
1
(0)

p300 HDR Plasmid (h)

sc-400055-HDRhHomology Directed RepairPuromycin
1
(0)

p300 Double Nickase Plasmid (h)

sc-400055-NIChGene KnockoutPuromycin
1
(0)

p300 Double Nickase Plasmid (h2)

sc-400055-NIC-2hGene KnockoutPuromycin
1
(0)

p300 CRISPR/Cas9 KO Plasmid (m)

sc-435902mGene KnockoutGFP0
(0)

p300 HDR Plasmid (m)

sc-435902-HDRmHomology Directed RepairPuromycin0
(0)

p300 Double Nickase Plasmid (m)

sc-435902-NICmGene KnockoutPuromycin0
(0)

p300 Double Nickase Plasmid (m2)

sc-435902-NIC-2mGene KnockoutPuromycin0
(0)

p300 CRISPR Activation Products

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p300 CRISPR Activation Plasmid (h)

sc-400055-ACThGene ActivationPuro, Blast, Hygro
1
(0)

p300 CRISPR Activation Plasmid (h2)

sc-400055-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

p300 Lentiviral Activation Particles (h)

sc-400055-LAChGene ActivationPuro, Blast, Hygro
1
(0)

p300 Lentiviral Activation Particles (h2)

sc-400055-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

p300 CRISPR Activation Plasmid (m)

sc-435902-ACTmGene ActivationPuro, Blast, Hygro0
(0)

p300 CRISPR Activation Plasmid (m2)

sc-435902-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

p300 Lentiviral Activation Particles (m)

sc-435902-LACmGene ActivationPuro, Blast, Hygro0
(0)

p300 Lentiviral Activation Particles (m2)

sc-435902-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

p300 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

p300 siRNA (h)

sc-29431hGene SilencingN/A
34
(1)

p300 shRNA Plasmid (h)

sc-29431-SHhGene SilencingPuromycin
34
(1)

p300 shRNA (h) Lentiviral Particles

sc-29431-VhGene SilencingPuromycin
34
(1)

p300 siRNA (m)

sc-29432mGene SilencingN/A
8
(0)

p300 shRNA Plasmid (m)

sc-29432-SHmGene SilencingPuromycin
8
(0)

p300 shRNA (m) Lentiviral Particles

sc-29432-VmGene SilencingPuromycin
8
(0)

p300 siRNA (r)

sc-270365rGene SilencingN/A
2
(0)

p300 shRNA Plasmid (r)

sc-270365-SHrGene SilencingPuromycin
2
(0)

p300 shRNA (r) Lentiviral Particles

sc-270365-VrGene SilencingPuromycin
2
(0)