p300 Antibody (NM11): sc-32244
- p300 Antibody (NM11) is a mouse monoclonal IgG2b κ, cited in 50 publications, provided at 200 µg/ml
- raised against affinity purified p300 of human origin
- Anti-p300 Antibody (NM11) is recommended for detection of p300 and CBP (CREB-binding protein) of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-p300 Antibody (NM11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for Gel Supershift and ChIP applications (sc-32244 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for p300 Antibody (NM11) for WB and IHC(P) applications. This reagent is now offered in a bundle with p300 Antibody (NM11) (see ordering information below).
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SEE ALSO...
p300 Antibody (NM11) is a mouse monoclonal IgG2b kappa light chain antibody designed to detect p300 protein, also known as EP300, as well as its closely related counterpart, CBP (CREB-binding protein or CREBBP), across mouse, rat, and human samples using western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). p300 protein functions as a critical transcriptional co-activator involved in regulating gene expression by modifying chromatin structure and facilitating the assembly of transcriptional complexes, which is essential for processes such as cell growth, differentiation, and apoptosis. Located primarily in the nucleus, p300 plays a pivotal role in gene regulation by interacting with various transcription factors and nuclear receptors, thereby influencing numerous cellular pathways and maintaining cellular homeostasis. Structurally, p300 is characterized by multiple domains, including bromodomains and HAT (histone acetyltransferase) domains, which are crucial for acetylating histones and other proteins, thereby modulating gene accessibility and transcriptional activity. p300 monoclonal antibody (NM11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® variants, providing versatility for different experimental applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p300 Antibody (NM11) | sc-32244 | 200 µg/ml | $322.00 | |||
p300 Antibody (NM11): m-IgG Fc BP-HRP Bundle | sc-525532 | 200 µg Ab; 10 µg BP | $361.00 | |||
p300 Antibody (NM11) X | sc-32244 X | 200 µg/0.1 ml | $322.00 | |||
p300 Antibody (NM11) AC | sc-32244 AC | 500 µg/ml, 25% agarose | $424.00 | |||
p300 Antibody (NM11) HRP | sc-32244 HRP | 200 µg/ml | $322.00 | |||
p300 Antibody (NM11) FITC | sc-32244 FITC | 200 µg/ml | $336.00 | |||
p300 Antibody (NM11) PE | sc-32244 PE | 200 µg/ml | $349.00 | |||
p300 Antibody (NM11) Alexa Fluor® 488 | sc-32244 AF488 | 200 µg/ml | $364.00 | |||
p300 Antibody (NM11) Alexa Fluor® 546 | sc-32244 AF546 | 200 µg/ml | $364.00 | |||
p300 Antibody (NM11) Alexa Fluor® 594 | sc-32244 AF594 | 200 µg/ml | $364.00 | |||
p300 Antibody (NM11) Alexa Fluor® 647 | sc-32244 AF647 | 200 µg/ml | $364.00 | |||
p300 Antibody (NM11) Alexa Fluor® 680 | sc-32244 AF680 | 200 µg/ml | $364.00 | |||
p300 Antibody (NM11) Alexa Fluor® 790 | sc-32244 AF790 | 200 µg/ml | $364.00 |