Date published: 2026-5-30

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p20-ARC Activators

p20-ARC activators are part of a distinct category of proteins that can bind to and interact with p20-ARC, a subunit of the Arp2/3 complex which plays an essential role in the regulation of actin cytoskeleton. The actin cytoskeleton, composed of actin proteins, is a key component of a cell's architecture and is responsible for many critical cellular functions including cell shape, movement, and division. Activators of p20-ARC can enhance its functionality, hence impacting actin polymerization and the overall structure and function of the actin cytoskeleton.

The mechanism by which p20-ARC activators function is predominantly centered around the modulation of actin dynamics. Through their interaction with p20-ARC, these activators can influence the initiation of new actin filament branches, a process that is crucial for the formation of cellular structures and the execution of cellular processes. The regulation of actin polymerization by these activators can have significant impact on cellular functions. The modulation of p20-ARC by its activators also plays an important role in cellular responses to various stimuli. Given that the actin cytoskeleton is integral to cellular movement and the uptake of external materials by the cell, p20-ARC activators are fundamental players in cellular response mechanisms. The exploration of p20-ARC activators is an active area of research, with much yet to be discovered about the specific ways in which they influence cellular structure and function.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Aminolevulinic Acid Hydrochloride Salt

5451-09-2sc-262399
sc-262399A
sc-262399B
sc-262399C
1 g
5 g
25 g
100 g
$41.00
$110.00
$320.00
$1400.00
2
(2)

Might indirectly activate p20-ARC through an upregulation of heme production.

Succinylacetone

51568-18-4sc-212963
sc-212963B
10 mg
100 mg
$336.00
$418.00
(1)

Could potentially activate p20-ARC through a compensatory response to diminished heme production.

Iron

7439-89-6sc-215190
sc-215190A
500 g
2 kg
$69.00
$180.00
(0)

Altering iron levels and thus the bioavailability of heme might indirectly trigger the activation of p20-ARC.

Hydroxyurea

127-07-1sc-29061
sc-29061A
5 g
25 g
$78.00
$260.00
18
(1)

Might indirectly activate p20-ARC through changes in heme demand or availability.

Deferoxamine mesylate

138-14-7sc-203331
sc-203331A
sc-203331B
sc-203331C
sc-203331D
1 g
5 g
10 g
50 g
100 g
$255.00
$1060.00
$2923.00
$4392.00
$8333.00
19
(1)

Might activate p20-ARC through effects on heme synthesis by chelating iron and reducing its availability.

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$63.00
$92.00
$250.00
$485.00
$1035.00
$2141.00
69
(5)

Could potentially activate p20-ARC through its effects on many cell signaling pathways.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$94.00
$213.00
33
(5)

Might activate p20-ARC through effects on dihydrofolate reductase inhibition and modulation of nucleotide biosynthesis.

Pyridoxine Hydrochloride

58-56-0sc-219674
10 mg
$42.00
(0)

Might indirectly activate p20-ARC through its effects on heme production as a cofactor for ALA synthase.

Lead

7439-92-1sc-250236
2 kg
$104.00
(0)

Might activate p20-ARC through a compensatory response to altered heme levels by disrupting heme biosynthesis.