p130 Cas Inhibitors
P130 Cas (Crk-associated substrate) inhibitors belong to a specific chemical class designed to target and modulate the activity of the p130 Cas protein. P130 Cas, also known as BCAR1 (Breast Cancer Anti-Estrogen Resistance 1), is a cytoplasmic scaffold protein that plays a crucial role in intracellular signaling pathways. This protein is involved in various cellular processes, including cell adhesion, migration, and proliferation, making it a key player in the regulation of cell behavior. P130 Cas acts as an adapter molecule, linking multiple signaling molecules and complexes together to coordinate cellular responses to extracellular signals. To achieve this, p130 Cas contains multiple protein-binding domains, such as SH2 (Src homology 2) and SH3 domains, which enable it to interact with a variety of proteins and participate in complex signal transduction networks.
P130 Cas inhibitors are designed to interfere with the normal functioning of p130 Cas by blocking its interactions with other proteins or disrupting its phosphorylation, which is essential for its activation. These inhibitors may target specific domains or sites on p130 Cas to inhibit its activity selectively. By modulating the activity of p130 Cas, these inhibitors have the ability to influence various cellular processes and signaling pathways that rely on p130 Cas-mediated interactions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Suberoylanilide Hydroxamic Acid is another histone deacetylase inhibitor that has the potential to alter gene expression by affecting chromatin structure. Its inhibition of histone deacetylase could potentially lead to reduced expression of p130 Cas. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-2′-Deoxycytidine is a DNA methyltransferase inhibitor. By inhibiting DNA methylation, it could potentially lead to a reduction in p130 Cas expression. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
MS-275 is a selective histone deacetylase inhibitor that can alter chromatin structure and gene expression. By inhibiting histone deacetylase, it has the potential to reduce the expression of p130 Cas. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
Romidepsin is a histone deacetylase inhibitor that can affect gene expression by changing the acetylation state of histones. Its potential to reduce the expression of p130 Cas is linked to its ability to modify chromatin structure. | ||||||
Belinostat | 414864-00-9 | sc-269851 sc-269851A | 10 mg 100 mg | $153.00 $561.00 | ||
Belinostat is another histone deacetylase inhibitor that can affect gene expression and chromatin structure. It has the potential to inhibit the expression of p130 Cas by altering the acetylation state of histones. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
Panobinostat is a potent histone deacetylase inhibitor that can alter chromatin structure and gene expression. Its ability to change the acetylation state of histones could potentially lead to reduced expression of p130 Cas. | ||||||
CI 994 | 112522-64-2 | sc-205245 sc-205245A | 10 mg 50 mg | $97.00 $525.00 | 1 | |
CI 994 is a histone deacetylase inhibitor with the potential to affect gene expression by modifying chromatin structure. It could potentially reduce the expression of p130 Cas through its effects on histone acetylation. | ||||||
JNJ-26481585 | 875320-29-9 | sc-364515 sc-364515A | 5 mg 50 mg | $321.00 $1224.00 | ||
JNJ-26481585 is a histone deacetylase inhibitor that can affect chromatin structure and gene expression. By altering the acetylation state of histones, it has the potential to reduce the expression of p130 Cas. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid is a histone deacetylase inhibitor that can alter gene expression by affecting chromatin structure. Its ability to change the acetylation state of histones could potentially lead to reduced expression of p130 Cas. | ||||||