Date published: 2026-3-3

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OXNAD1 Inhibitors

OXNAD1 inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the OXNAD1 protein, also known as oxidoreductase NAD-binding domain-containing protein 1. OXNAD1 belongs to a family of enzymes involved in redox reactions, which play essential roles in maintaining cellular homeostasis by facilitating electron transfer during metabolic processes. This protein is particularly important in regulating cellular energy production, as it participates in reactions that are crucial for the oxidation-reduction balance in cells. By inhibiting OXNAD1, these compounds disrupt its enzymatic functions, affecting the efficiency of redox processes and altering cellular energy metabolism. This can lead to changes in the overall oxidative state of the cell, impacting various downstream processes such as metabolic flux and the maintenance of cellular redox balance.

The study of OXNAD1 inhibitors is critical for understanding the broader role of this protein in cellular metabolism and redox regulation. By blocking OXNAD1, researchers can explore how inhibiting specific oxidoreductases affects electron transport chains, metabolic pathways, and the maintenance of cellular oxidative stress responses. OXNAD1 inhibitors allow scientists to dissect the role of redox reactions in cellular processes such as respiration, biosynthesis, and detoxification. Moreover, these inhibitors provide insights into how OXNAD1 interacts with other proteins involved in maintaining the oxidative environment of the cell, offering a deeper understanding of the regulation of metabolic networks and cellular energy production. Through these studies, OXNAD1 inhibitors help clarify the essential functions of redox enzymes in overall cellular physiology and energy dynamics.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Auranofin

34031-32-8sc-202476
sc-202476A
sc-202476B
25 mg
100 mg
2 g
$153.00
$214.00
$4000.00
39
(2)

Auranofin inhibits the Oxidoreductase NAD-binding domain-containing protein 1 by binding to the cysteine residues in the active site, disrupting the normal redox activity of the protein.

Allopurinol

315-30-0sc-207272
25 g
$131.00
(0)

Allopurinol inhibits the activity of Oxidoreductase NAD-binding domain-containing protein 1 by competitively inhibiting the enzyme's activity, leading to a decrease in the production of uric acid, which is a downstream product of the enzyme's activity.

Methimazole

60-56-0sc-205747
sc-205747A
10 g
25 g
$70.00
$112.00
4
(0)

Methimazole serves as an inhibitor of Oxidoreductase NAD-binding domain-containing protein 1 by interfering with the thyroid hormone synthesis, which is partially regulated by the redox state maintained by this protein.

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$53.00
$89.00
7
(1)

Disulfiram inhibits Oxidoreductase NAD-binding domain-containing protein 1 by modifying the thiol groups in the protein, which are essential for its catalytic activity.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Chloroquine is known to inhibit Oxidoreductase NAD-binding domain-containing protein 1 by increasing the pH of intracellular compartments, which affects the enzyme's stability and function.

Vitamin K3

58-27-5sc-205990B
sc-205990
sc-205990A
sc-205990C
sc-205990D
5 g
10 g
25 g
100 g
500 g
$26.00
$36.00
$47.00
$136.00
$455.00
3
(1)

Vitamin K3 inhibits Oxidoreductase NAD-binding domain-containing protein 1 by acting as a redox-cycling compound that depletes intracellular NAD(P)H pools, affecting the catalytic cycle of the protein.

Methylene blue

61-73-4sc-215381B
sc-215381
sc-215381A
25 g
100 g
500 g
$43.00
$104.00
$328.00
3
(1)

Methylene Blue inhibits Oxidoreductase NAD-binding domain-containing protein 1 by accepting electrons during redox reactions, which can interfere with the protein's normal electron transfer processes.

Oltipraz

64224-21-1sc-205777
sc-205777A
500 mg
1 g
$286.00
$622.00
(1)

Oltipraz inhibits Oxidoreductase NAD-binding domain-containing protein 1 by modulating the Keap1-Nrf2 pathway, which is involved in the cellular antioxidant response and may affect the protein's function due to changes in cellular redox homeostasis.

Phenylarsine oxide

637-03-6sc-3521
250 mg
$41.00
4
(1)

Phenylarsine Oxide inhibits Oxidoreductase NAD-binding domain-containing protein 1 by binding to vicinal dithiols and disrupting protein function, including proteins involved in redox processes.

Ritonavir

155213-67-5sc-208310
10 mg
$124.00
7
(1)

Ritonavir inhibits Oxidoreductase NAD-binding domain-containing protein 1 by inhibiting the proteasome, which can lead to an altered cellular redox environment and consequently affect the function of this oxidoreductase protein.