OXA1L Activators
The OXA1L Activators are a class of chemical compounds that are known to enhance the function of the OXA1L protein, a mitochondrial protein involved in the insertion of proteins into the mitochondrial inner membrane. These activators can enhance OXA1L's function indirectly by either promoting mitochondrial biogenesis, enhancing mitochondrial health, or increasing the efficiency of the electron transport chain. This is because an increase in mitochondrial biogenesis or function can lead to an increased demand for the protein insertion activity of OXA1L. For instance, compounds such as Retinoic Acid, Rosiglitazone, and Resveratrol are known to promote mitochondrial biogenesis. By increasing the number of mitochondria, these compounds indirectly enhance the function of OXA1L by increasing the demand for protein insertion into the mitochondrial inner membrane.
Similarly,compounds such as Coenzyme Q10 and MitoQ enhance mitochondrial health and functionality, indirectly enhancing the function of OXA1L. An increase in mitochondrial health and function can lead to an increased demand for the protein insertion activity of OXA1L. On the other hand, compounds like Metformin and AICAR, which are activators of AMPK, can enhance the function of OXA1L by promoting mitochondrial biogenesis and function, leading to an increased demand for OXA1L's protein insertion role. Likewise, PPARγ agonists such as Rosiglitazone, Troglitazone, and Pioglitazone, as well as the pan-PPAR agonist Bezafibrate, can increase mitochondrial biogenesis, indirectly enhancing the function of OXA1L by increasing the demand for its protein insertion function. Lastly, the PGC-1α agonist SR-18292 and the natural flavonoid Epicatechin can also enhance the function of OXA1L by promoting mitochondrial biogenesis and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid is an active metabolite of Vitamin A, which is known to influence mitochondrial biogenesis. It can enhance the function of OXA1L by promoting the expression of mitochondrial proteins, thus potentially promoting the insertion of proteins into the mitochondrial inner membrane, a process that OXA1L is directly involved in. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Coenzyme Q10 is an essential cofactor in the mitochondrial electron transport chain. It can indirectly enhance the function of OXA1L by increasing the overall efficiency of electron transport and ATP production in mitochondria, potentially leading to an increased demand for OXA1L's function of inserting proteins into the mitochondrial inner membrane. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a natural compound that is known to activate SIRT1, a protein deacetylase that promotes mitochondrial biogenesis. By activating SIRT1, resveratrol can indirectly enhance the function of OXA1L by increasing the demand for the insertion of proteins into the mitochondrial inner membrane. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Rosiglitazone is a PPARγ agonist that can promote mitochondrial biogenesis. By enhancing mitochondrial biogenesis, Rosiglitazone can indirectly enhance the function of OXA1L by increasing the demand for its protein insertion activity. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
Metformin is an AMPK activator. AMPK activation increases mitochondrial biogenesis and function, which in turn may enhance the function of OXA1L due to increased demand for protein insertion into the mitochondrial inner membrane. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR is an AMPK activator. Similar to Metformin, AICAR can enhance the function of OXA1L by promoting mitochondrial biogenesis and function, leading to increased demand for OXA1L's protein insertion role. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
MitoQ is a targeted antioxidant to mitochondria that can enhance mitochondrial health and functionality, potentially leading to increased demand for OXA1L's role in protein insertion. | ||||||
(−)Epicatechin | 490-46-0 | sc-205672 sc-205672A | 1 mg 5 mg | $50.00 $135.00 | ||
Epicatechin is a natural flavonoid that can enhance mitochondrial biogenesis and function, potentially leading to an increased need for OXA1L's protein insertion activity. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Bezafibrate is a pan-PPAR agonist. By activating the PPAR pathway, bezafibrate can increase mitochondrial biogenesis and hence potentially enhance OXA1L's function by elevating the demand for protein insertion into the mitochondrial inner membrane. | ||||||
Troglitazone | 97322-87-7 | sc-200904 sc-200904B sc-200904A | 5 mg 10 mg 25 mg | $108.00 $200.00 $426.00 | 9 | |
Troglitazone is a PPARγ agonist that can increase mitochondrial biogenesis, which can indirectly enhance the function of OXA1L due to the increased need for protein insertion into the mitochondrial inner membrane. | ||||||